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GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 [ Homo sapiens (human) ]

Gene ID: 57452, updated on 13-Mar-2020

Summary

Official Symbol
GALNT16provided by HGNC
Official Full Name
polypeptide N-acetylgalactosaminyltransferase 16provided by HGNC
Primary source
HGNC:HGNC:23233
See related
Ensembl:ENSG00000100626 MIM:615132
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GALNTL1; GALNACT16; GalNAc-T16
Expression
Broad expression in brain (RPKM 7.7), heart (RPKM 6.0) and 21 other tissues See more
Orthologs

Genomic context

See GALNT16 in Genome Data Viewer
Location:
14q24.1
Exon count:
20
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (69259546..69379904)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (69726681..69821190)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 5 Neighboring gene DEAD-box helicase 18 pseudogene 1 Neighboring gene uncharacterized LOC105370550 Neighboring gene exonuclease 3'-5' domain containing 2 Neighboring gene uncharacterized LOC105370549 Neighboring gene solute carrier family 39 member 9 Neighboring gene ERH mRNA splicing and mitosis factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1130, MGC141855

Gene Ontology Provided by GOA

Function Evidence Code Pubs
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
polypeptide N-acetylgalactosaminyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
protein O-linked glycosylation via serine IDA
Inferred from Direct Assay
more info
PubMed 
protein O-linked glycosylation via threonine IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
polypeptide N-acetylgalactosaminyltransferase 16
Names
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
galNAc-T-like protein 1
polypeptide GalNAc transferase 16
polypeptide GalNAc transferase-like protein 1
polypeptide N-acetylgalactosaminyltransferase-like protein 1
pp-GaNTase-like protein 1
protein-UDP acetylgalactosaminyltransferase-like protein 1
putative polypeptide N-acetylgalactosaminyltransferase-like protein 1
NP_001161840.1
NP_065743.2
XP_011535307.1
XP_011535308.1
XP_011535309.1
XP_016876987.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168368.2NP_001161840.1  polypeptide N-acetylgalactosaminyltransferase 16

    See identical proteins and their annotated locations for NP_001161840.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK091426, AK289745, AL157996, AL359317, DA493083
    Consensus CDS
    CCDS32107.1
    UniProtKB/Swiss-Prot
    Q8N428
    UniProtKB/TrEMBL
    Q68VJ8
    Related
    ENSP00000402970.3, ENST00000448469.8
    Conserved Domains (2) summary
    cd02510
    Location:126420
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:441543
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
  2. NM_020692.3NP_065743.2  polypeptide N-acetylgalactosaminyltransferase 16

    See identical proteins and their annotated locations for NP_065743.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL157996, AL359317, BC098578, BG059801, DA493083
    Consensus CDS
    CCDS32107.1
    UniProtKB/Swiss-Prot
    Q8N428
    UniProtKB/TrEMBL
    Q68VJ8
    Related
    ENSP00000336729.4, ENST00000337827.8
    Conserved Domains (2) summary
    cd02510
    Location:126420
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:441543
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    69259546..69379904
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017021498.1XP_016876987.1  polypeptide N-acetylgalactosaminyltransferase 16 isoform X1

    UniProtKB/Swiss-Prot
    Q8N428
    UniProtKB/TrEMBL
    Q68VJ8
    Conserved Domains (2) summary
    cd02510
    Location:126420
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:441543
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
  2. XM_011537005.2XP_011535307.1  polypeptide N-acetylgalactosaminyltransferase 16 isoform X1

    See identical proteins and their annotated locations for XP_011535307.1

    UniProtKB/Swiss-Prot
    Q8N428
    UniProtKB/TrEMBL
    Q68VJ8
    Related
    ENSP00000451200.1, ENST00000553669.1
    Conserved Domains (2) summary
    cd02510
    Location:126420
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:441543
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
  3. XM_011537006.3XP_011535308.1  polypeptide N-acetylgalactosaminyltransferase 16 isoform X1

    See identical proteins and their annotated locations for XP_011535308.1

    UniProtKB/Swiss-Prot
    Q8N428
    UniProtKB/TrEMBL
    Q68VJ8
    Conserved Domains (2) summary
    cd02510
    Location:126420
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:441543
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
  4. XM_011537007.3XP_011535309.1  polypeptide N-acetylgalactosaminyltransferase 16 isoform X2

    Related
    ENSP00000451420.1, ENST00000553471.6
    Conserved Domains (3) summary
    cd02510
    Location:126420
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    COG0463
    Location:126222
    WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
    cd00161
    Location:441514
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
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