Format

Send to:

Choose Destination

Marchf7 membrane associated ring-CH-type finger 7 [ Mus musculus (house mouse) ]

Gene ID: 57438, updated on 16-Oct-2021

Summary

Official Symbol
Marchf7provided by MGI
Official Full Name
membrane associated ring-CH-type finger 7provided by MGI
Primary source
MGI:MGI:1931053
See related
Ensembl:ENSMUSG00000026977
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Axo; Axot; March7; Gtrgeo17
Expression
Ubiquitous expression in CNS E11.5 (RPKM 13.5), CNS E18 (RPKM 13.4) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Marchf7 in Genome Data Viewer
Location:
2; 2 C1.1
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (60040086..60079562)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (60209936..60248385)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (60047993..60086442)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene bromodomain adjacent to zinc finger domain, 2B Neighboring gene predicted gene 13570 Neighboring gene lactate dehydrogenase A, pseudogene Neighboring gene ribosomal protein L10A, pseudogene 4 Neighboring gene CD302 antigen Neighboring gene lymphocyte antigen 75 Neighboring gene predicted gene 13571

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables MDM2/MDM4 family protein binding ISO
Inferred from Sequence Orthology
more info
 
enables enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ubiquitin binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ubiquitin conjugating enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
E3 ubiquitin-protein ligase MARCHF7
Names
E3 ubiquitin-protein ligase MARCH7
MARCH-VII
RING-type E3 ubiquitin transferase MARCH7
RING-type E3 ubiquitin transferase MARCHF7
axotrophin
gene trap ROSA b-geo 17
membrane-associated RING finger protein 7
membrane-associated RING-CH protein VII
membrane-associated ring finger (C3HC4) 7
NP_065600.1
XP_036018314.1
XP_036018315.1
XP_036018316.1
XP_036018317.1
XP_036018318.1
XP_036018319.1
XP_036018320.1
XP_036018322.1
XP_036018323.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020575.2NP_065600.1  E3 ubiquitin-protein ligase MARCHF7

    See identical proteins and their annotated locations for NP_065600.1

    Status: PROVISIONAL

    Source sequence(s)
    AL935326
    Consensus CDS
    CCDS16057.1
    UniProtKB/Swiss-Prot
    Q9WV66
    Related
    ENSMUSP00000099809.5, ENSMUST00000102748.11
    Conserved Domains (2) summary
    cd00162
    Location:554609
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:554612
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    60040086..60079562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162421.1XP_036018314.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

    Conserved Domains (2) summary
    cd00162
    Location:554609
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:554612
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  2. XM_036162423.1XP_036018316.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    Conserved Domains (2) summary
    cd00162
    Location:554609
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:554612
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  3. XM_036162430.1XP_036018323.1  E3 ubiquitin-protein ligase MARCHF7 isoform X7

    Conserved Domains (2) summary
    cd00162
    Location:263318
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:263321
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  4. XM_036162425.1XP_036018318.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    Conserved Domains (2) summary
    cd00162
    Location:554609
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:554612
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  5. XM_036162426.1XP_036018319.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    Conserved Domains (2) summary
    cd00162
    Location:554609
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:554612
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  6. XM_036162427.1XP_036018320.1  E3 ubiquitin-protein ligase MARCHF7 isoform X5

    Conserved Domains (2) summary
    cd00162
    Location:263318
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:263321
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  7. XM_036162422.1XP_036018315.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

    Conserved Domains (2) summary
    cd00162
    Location:554609
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:554612
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  8. XM_036162424.1XP_036018317.1  E3 ubiquitin-protein ligase MARCHF7 isoform X3

    Related
    ENSMUSP00000099808.2, ENSMUST00000102747.8
    Conserved Domains (2) summary
    cd00162
    Location:554609
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:554612
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  9. XM_036162429.1XP_036018322.1  E3 ubiquitin-protein ligase MARCHF7 isoform X6

    Conserved Domains (2) summary
    cd00162
    Location:263318
    RING_Ubox; RING-CH finger (C4HC3-type) [structural motif]
    cl17238
    Location:263321
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

RNA

  1. XR_004940676.1 RNA Sequence

  2. XR_004940675.1 RNA Sequence

  3. XR_004940674.1 RNA Sequence

  4. XR_004940677.1 RNA Sequence

Support Center