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C3orf14 chromosome 3 open reading frame 14 [ Homo sapiens (human) ]

Gene ID: 57415, updated on 5-Aug-2018

Summary

Official Symbol
C3orf14provided by HGNC
Official Full Name
chromosome 3 open reading frame 14provided by HGNC
Primary source
HGNC:HGNC:25024
See related
Ensembl:ENSG00000114405 Vega:OTTHUMG00000158704
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HT021
Expression
Broad expression in brain (RPKM 5.7), testis (RPKM 2.9) and 21 other tissues See more
Orthologs

Genomic context

See C3orf14 in Genome Data Viewer
Location:
3p14.2
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (62318973..62336213)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (62304648..62321888)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase, receptor type G Neighboring gene uncharacterized LOC105377116 Neighboring gene PTPRG antisense RNA 1 Neighboring gene VISTA enhancer hs434 Neighboring gene FEZ family zinc finger 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
uncharacterized protein C3orf14

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291941.1NP_001278870.1  uncharacterized protein C3orf14 isoform a

    See identical proteins and their annotated locations for NP_001278870.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC092502, AF236158, BE047745, DA783189
    Consensus CDS
    CCDS2896.1
    UniProtKB/Swiss-Prot
    Q9HBI5
    UniProtKB/TrEMBL
    A0A024R330
    Related
    ENSP00000419977.1, OTTHUMP00000213296, ENST00000462069.5, OTTHUMT00000351810
    Conserved Domains (1) summary
    pfam15134
    Location:1109
    DUF4570; Domain of unknown function (DUF4570)
  2. NM_001291942.1NP_001278871.1  uncharacterized protein C3orf14 isoform a

    See identical proteins and their annotated locations for NP_001278871.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC092502, BE047745, BU568674, DA783189
    Consensus CDS
    CCDS2896.1
    UniProtKB/Swiss-Prot
    Q9HBI5
    UniProtKB/TrEMBL
    A0A024R330
    Related
    ENSP00000232519.5, OTTHUMP00000213298, ENST00000232519.9, OTTHUMT00000351812
    Conserved Domains (1) summary
    pfam15134
    Location:1109
    DUF4570; Domain of unknown function (DUF4570)
  3. NM_001291943.1NP_001278872.1  uncharacterized protein C3orf14 isoform b

    See identical proteins and their annotated locations for NP_001278872.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, the 3' UTR, and the 3' coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    DA615061, DA783189
    Conserved Domains (1) summary
    pfam15134
    Location:159
    DUF4570; Domain of unknown function (DUF4570)
  4. NM_020685.4NP_065736.1  uncharacterized protein C3orf14 isoform a

    See identical proteins and their annotated locations for NP_065736.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC092502, AK313915, BE047745
    Consensus CDS
    CCDS2896.1
    UniProtKB/Swiss-Prot
    Q9HBI5
    UniProtKB/TrEMBL
    A0A024R330
    Related
    ENSP00000418086.1, OTTHUMP00000213295, ENST00000494481.5, OTTHUMT00000351807
    Conserved Domains (1) summary
    pfam15134
    Location:1109
    DUF4570; Domain of unknown function (DUF4570)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    62318973..62336213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017006931.1XP_016862420.1  uncharacterized protein C3orf14 isoform X1

    UniProtKB/Swiss-Prot
    Q9HBI5
    UniProtKB/TrEMBL
    A0A024R330
    Related
    ENSP00000438275.1, ENST00000542214.2
    Conserved Domains (1) summary
    pfam15134
    Location:1109
    DUF4570; Domain of unknown function (DUF4570)
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