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CRHR1 corticotropin releasing hormone receptor 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574095, updated on 10-Feb-2026
Official Symbol
CRHR1provided by VGNC
Official Full Name
corticotropin releasing hormone receptor 1provided by VGNC
Primary source
VGNC:VGNC:81184
See related
Ensembl:ENSMMUG00000004108
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
CRF1
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See CRHR1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 16 NC_133421.1 (70693873..70745597)
103 previous assembly Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (57581792..57638936)

Chromosome 16 - NC_133421.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144335839 Neighboring gene putative uncharacterized protein encoded by CRHR1-IT1 Neighboring gene uncharacterized LOC114673220 Neighboring gene uncharacterized LOC144335835 Neighboring gene signal peptide peptidase like 2C Neighboring gene uncharacterized LOC144335818 Neighboring gene microtubule associated protein tau

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression. Rogers J, et al. Mol Psychiatry, 2013 Jun. PMID 23147386, Free PMC Article
  2. Monkey corticotropin-releasing factor1 receptor: Complementary DNA cloning and pharmacological characterization. Oshida Y, et al. Life Sci, 2004 Feb 27. PMID 14761672
  3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotrophin-releasing factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotropin-releasing hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotropin-releasing hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
corticotropin-releasing factor receptor 1
Names
CRF-R-1
CRF-R1
CRFR-1
corticotropin releasing factor receptor type 1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032803.1 → NP_001027975.1  corticotropin-releasing factor receptor 1 precursor

    See identical proteins and their annotated locations for NP_001027975.1

    Status: PROVISIONAL

    Source sequence(s)
    AB078141
    UniProtKB/Swiss-Prot
    Q76LL8
    UniProtKB/TrEMBL
    F6Z590
    Related
    ENSMMUP00000045328.2, ENSMMUT00000067471.2
    Conserved Domains (2) summary
    smart00008
    Location:40 → 111
    HormR; Domain present in hormone receptors
    cd15445
    Location:116 → 380
    7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133421.1 Reference T2T-MMU8v2.0

    Range
    70693873..70745597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028835446.2 → XP_028691279.1  corticotropin-releasing factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R687, F6Z590
    Related
    ENSMMUP00000055825.1
    Conserved Domains (2) summary
    smart00008
    Location:40 → 111
    HormR; Domain present in hormone receptors
    cd15445
    Location:116 → 409
    7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors

  2. XM_077968450.1 → XP_077824576.1  corticotropin-releasing factor receptor 1 isoform X2

    UniProtKB/TrEMBL
    F6Z590

  3. XM_077968451.1 → XP_077824577.1  corticotropin-releasing factor receptor 1 isoform X3

    UniProtKB/TrEMBL
    F6Z590

  4. XM_028835445.2 → XP_028691278.1  corticotropin-releasing factor receptor 1 isoform X6

    UniProtKB/TrEMBL
    H9F7K1
    Conserved Domains (1) summary
    cd15445
    Location:15 → 279
    7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors

  5. XM_028835444.2 → XP_028691277.1  corticotropin-releasing factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    F6Z517, F6Z590
    Related
    ENSMMUP00000005497.3
    Conserved Domains (2) summary
    cd15445
    Location:76 → 340
    7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors
    cl02422
    Location:28 → 71
    HRM; Hormone receptor domain

  6. XM_077968452.1 → XP_077824578.1  corticotropin-releasing factor receptor 1 isoform X5

    UniProtKB/TrEMBL
    F6Z590

  7. XM_015119720.3 → XP_014975206.1  corticotropin-releasing factor receptor 1 isoform X7

    UniProtKB/TrEMBL
    H9F7K1
    Conserved Domains (1) summary
    pfam00002
    Location:3 → 184
    7tm_2; 7 transmembrane receptor (Secretin family)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q76LL8.1 GenPept UniProtKB/Swiss-Prot:Q76LL8

Gene LinkOut

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