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inaF-C inaF-C [ Drosophila melanogaster (fruit fly) ]

Gene ID: 5740497, updated on 5-Jul-2025
Official Symbol
inaF-Cprovided by FlyBase
Official Full Name
inaF-Cprovided by FlyBase
Primary source
FLYBASE:FBgn0085350
Locus tag
Dmel_CG34321
See related
AllianceGenome:FB:FBgn0085350
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG34321; Dmel\CG34321; inaF; InaF; INAF; INAF-C
Summary
Enables calcium channel regulator activity. Involved in response to light stimulus. Located in rhabdomere. Is expressed in adult head. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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Try the new Transcripts and proteins table
See inaF-C in Genome Data Viewer
Location:
10D8-10E1; 1-36 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11726390..11731765, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11620423..11625798, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pretaporter Neighboring gene Transport and Golgi organization 10 Neighboring gene uncharacterized protein Neighboring gene inaF-D Neighboring gene inaF-B Neighboring gene inaF-A Neighboring gene pseudo Neighboring gene miniature Neighboring gene uncharacterized protein

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus. Cheng Y, et al. Proc Natl Acad Sci U S A, 2007 Nov 6. PMID 17968007, Free PMC Article
  2. INAF, a protein required for transient receptor potential Ca(2+) channel function. Li C, et al. Proc Natl Acad Sci U S A, 1999 Nov 9. PMID 10557345, Free PMC Article
  3. Distinct TRP channels are required for warm and cool avoidance in Drosophila melanogaster. Rosenzweig M, et al. Proc Natl Acad Sci U S A, 2008 Sep 23. PMID 18787131, Free PMC Article
  4. Nascent-Seq analysis of Drosophila cycling gene expression. Rodriguez J, et al. Proc Natl Acad Sci U S A, 2013 Jan 22. PMID 23297234, Free PMC Article
  5. Subcellular translocation of the eGFP-tagged TRPL channel in Drosophila photoreceptors requires activation of the phototransduction cascade. Meyer NE, et al. J Cell Sci, 2006 Jun 15. PMID 16735439, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A Family of Auxiliary Subunits of the TRP Cation Channel Encoded by the Complex inaF Locus.
    Title: A Family of Auxiliary Subunits of the TRP Cation Channel Encoded by the Complex inaF Locus.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium channel regulator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of membrane potential ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in response to light stimulus IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in rhabdomere IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
inaF-C
Names
CG34321-PA
inaF-C-PA

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11726390..11731765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103489.2 → NP_001096959.1  inaF-C

    See identical proteins and their annotated locations for NP_001096959.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6IIF2
    Conserved Domains (1) summary
    pfam15018
    Location:92 → 126
    InaF-motif; TRP-interacting helix
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IIF2 Q6IIF2

Gene LinkOut

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