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DHFRP1 dihydrofolate reductase pseudogene 1 [ Homo sapiens (human) ]

Gene ID: 573971, updated on 13-May-2022

Summary

Official Symbol
DHFRP1provided by HGNC
Official Full Name
dihydrofolate reductase pseudogene 1provided by HGNC
Primary source
HGNC:HGNC:2862
See related
AllianceGenome:HGNC:2862
Gene type
pseudo
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Enables anion binding activity; dihydrofolate reductase activity; and nucleic acid binding activity. Involved in dihydrofolate metabolic process; negative regulation of translation; and pteridine-containing compound biosynthetic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See DHFRP1 in Genome Data Viewer
Location:
18q11.2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (26167862..26171357, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (26362502..26365997, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (23747826..23751321, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene SS18 subunit of BAF chromatin remodeling complex Neighboring gene ribosomal protein S24 pseudogene 18 Neighboring gene proteasome 20S subunit alpha 8 Neighboring gene nucleophosmin 1 pseudogene 2 Neighboring gene TATA-box binding protein associated factor 4b Neighboring gene SINHCAF pseudogene 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Other Names

  • hDHFR-psi 3

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables NADP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables NADPH binding IDA
Inferred from Direct Assay
more info
PubMed 
enables dihydrofolate reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables dihydrofolate reductase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables dihydrofolate reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables dihydrofolate reductase activity NAS
Non-traceable Author Statement
more info
PubMed 
enables folic acid binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA regulatory element binding translation repressor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables sequence-specific mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in axon regeneration ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in dihydrofolate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dihydrofolate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in folic acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in folic acid metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in glycine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of translation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in one-carbon metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of nitric-oxide synthase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of removal of superoxide radicals ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in response to methotrexate IEA
Inferred from Electronic Annotation
more info
 
involved_in tetrahydrobiopterin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in tetrahydrobiopterin biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in tetrahydrofolate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tetrahydrofolate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in tetrahydrofolate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol TAS
Traceable Author Statement
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_005427.7 

    Range
    101..3596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    26167862..26171357 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    26362502..26365997 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)