Format

Send to:

Choose Destination

ZNF286A zinc finger protein 286A [ Homo sapiens (human) ]

Gene ID: 57335, updated on 12-Oct-2019

Summary

Official Symbol
ZNF286Aprovided by HGNC
Official Full Name
zinc finger protein 286Aprovided by HGNC
Primary source
HGNC:HGNC:13501
See related
Ensembl:ENSG00000187607
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF286
Expression
Ubiquitous expression in ovary (RPKM 4.0), endometrium (RPKM 3.2) and 24 other tissues See more
Orthologs

Genomic context

See ZNF286A in Genome Data Viewer
Location:
17p12
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (15699752..15720787)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (15602891..15624101)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene proximal CMT1A-REP Neighboring gene CMT1A duplicated region transcript 1 Neighboring gene tripartite motif containing 16 Neighboring gene zinc finger protein 29, pseudogene Neighboring gene ubiquitin conjugating enzyme E2 S pseudogene 1 Neighboring gene uncharacterized LOC105371560 Neighboring gene uncharacterized LOC105371559 Neighboring gene TBC1 domain family member 26

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1874, MGC149627, MGC156181

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 286A
Names
zinc finger protein ZNF286

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130842.2NP_001124314.1  zinc finger protein 286A isoform 2

    See identical proteins and their annotated locations for NP_001124314.1

    Status: VALIDATED

    Source sequence(s)
    AC005324, AF217226, AK315062, BU687070
    Consensus CDS
    CCDS11172.1
    UniProtKB/Swiss-Prot
    Q9HBT8
    UniProtKB/TrEMBL
    B2RCD9
    Related
    ENSP00000464063.1, ENST00000583566.6
    Conserved Domains (6) summary
    smart00349
    Location:4598
    KRAB; krueppel associated box
    COG5048
    Location:352507
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:354376
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:4580
    KRAB; KRAB box
    pfam13465
    Location:424449
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001288642.2NP_001275571.1  zinc finger protein 286A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    UniProtKB/Swiss-Prot
    Q9HBT8
    Conserved Domains (6) summary
    smart00349
    Location:88141
    KRAB; krueppel associated box
    COG5048
    Location:395550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:427447
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:397419
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:88123
    KRAB; KRAB box
    pfam13465
    Location:467492
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001288643.2NP_001275572.1  zinc finger protein 286A isoform 3

    See identical proteins and their annotated locations for NP_001275572.1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    Consensus CDS
    CCDS73997.1
    UniProtKB/Swiss-Prot
    Q9HBT8
    Related
    ENSP00000466154.1, ENST00000593105.5
    Conserved Domains (6) summary
    smart00349
    Location:3588
    KRAB; krueppel associated box
    COG5048
    Location:342497
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:374394
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:344366
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:3570
    KRAB; KRAB box
    pfam13465
    Location:414439
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001288644.2NP_001275573.2  zinc finger protein 286A isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC005324
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_001288645.2NP_001275574.1  zinc finger protein 286A isoform 5

    See identical proteins and their annotated locations for NP_001275574.1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    UniProtKB/Swiss-Prot
    Q9HBT8
    UniProtKB/TrEMBL
    A1A525
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. NM_001288646.2NP_001275575.1  zinc finger protein 286A isoform 5

    See identical proteins and their annotated locations for NP_001275575.1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    UniProtKB/Swiss-Prot
    Q9HBT8
    UniProtKB/TrEMBL
    A1A525
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. NM_001288647.2NP_001275576.1  zinc finger protein 286A isoform 5

    See identical proteins and their annotated locations for NP_001275576.1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    UniProtKB/Swiss-Prot
    Q9HBT8
    UniProtKB/TrEMBL
    A1A525
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. NM_001288648.2NP_001275577.1  zinc finger protein 286A isoform 5

    See identical proteins and their annotated locations for NP_001275577.1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    UniProtKB/Swiss-Prot
    Q9HBT8
    UniProtKB/TrEMBL
    A1A525
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. NM_001288649.2NP_001275578.1  zinc finger protein 286A isoform 5

    See identical proteins and their annotated locations for NP_001275578.1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    UniProtKB/Swiss-Prot
    Q9HBT8
    UniProtKB/TrEMBL
    A1A525
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. NM_001369436.1NP_001356365.1  zinc finger protein 286A isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC005324
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  11. NM_001369437.1NP_001356366.1  zinc finger protein 286A isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC005324
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  12. NM_001369438.1NP_001356367.1  zinc finger protein 286A isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC005324
    Conserved Domains (2) summary
    COG5048
    Location:240395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  13. NM_001369440.1NP_001356369.1  zinc finger protein 286A isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC005324
    Conserved Domains (3) summary
    smart00349
    Location:147
    KRAB; krueppel associated box
    COG5048
    Location:301456
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:333353
    ZF_C2H2; C2H2 Zn finger [structural motif]
  14. NM_020652.3NP_065703.1  zinc finger protein 286A isoform 2

    See identical proteins and their annotated locations for NP_065703.1

    Status: VALIDATED

    Source sequence(s)
    AC005324
    Consensus CDS
    CCDS11172.1
    UniProtKB/Swiss-Prot
    Q9HBT8
    Related
    ENSP00000397163.1, ENST00000421016.5
    Conserved Domains (6) summary
    smart00349
    Location:4598
    KRAB; krueppel associated box
    COG5048
    Location:352507
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:354376
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:4580
    KRAB; KRAB box
    pfam13465
    Location:424449
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    15699752..15720787
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center