U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 [ Mus musculus (house mouse) ]

Gene ID: 57279, updated on 8-Dec-2022

Summary

Official Symbol
Slc25a20provided by MGI
Official Full Name
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20provided by MGI
Primary source
MGI:MGI:1928738
See related
Ensembl:ENSMUSG00000032602 AllianceGenome:MGI:1928738
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CAC; Cact; mCAC; 1110007P09Rik
Summary
Predicted to enable acyl carnitine transmembrane transporter activity. Acts upstream of or within in utero embryonic development. Located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 46.4), colon adult (RPKM 29.5) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Slc25a20 in Genome Data Viewer
Location:
9; 9 F2
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (108539335..108561841)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (108662136..108684642)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) Neighboring gene ariadne RBR E3 ubiquitin protein ligase 2 Neighboring gene protein kinase, cAMP dependent regulatory, type II alpha Neighboring gene predicted gene, 24259 Neighboring gene inositol hexaphosphate kinase 2 Neighboring gene predicted gene, 23034

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acyl carnitine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables acyl carnitine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in carnitine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in carnitine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrial envelope IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrial inner membrane HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial carnitine/acylcarnitine carrier protein
NP_065266.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020520.5NP_065266.1  mitochondrial carnitine/acylcarnitine carrier protein

    See identical proteins and their annotated locations for NP_065266.1

    Status: VALIDATED

    Source sequence(s)
    CT571271
    Consensus CDS
    CCDS23535.1
    UniProtKB/Swiss-Prot
    Q3U801, Q9Z2Z6
    UniProtKB/TrEMBL
    A0A8C6G5C5
    Related
    ENSMUSP00000035222.6, ENSMUST00000035222.6
    Conserved Domains (1) summary
    pfam00153
    Location:106198
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    108539335..108561841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)