b3galt6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: b3galt6provided by ZNC
Official Full Name: UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-101104-13
See related: Ensembl:ENSDARG00000038414 AllianceGenome:ZFIN:ZDB-GENE-101104-13
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable galactosylxylosylprotein 3-beta-galactosyltransferase activity. Predicted to be involved in glycosaminoglycan biosynthetic process and protein O-linked glycosylation. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Used to study Ehlers-Danlos syndrome. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome spondylodysplastic type 2 and spondyloepimetaphyseal dysplasia with joint laxity type 1. Orthologous to human B3GALT6 (beta-1,3-galactosyltransferase 6). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	11	NC_133186.1 (2730425..2735712)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (2685121..2690933)

Chromosome 11 - NC_133186.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables galactosylxylosylprotein 3-beta-galactosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables galactosylxylosylprotein 3-beta-galactosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables hexosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glycosaminoglycan biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycosaminoglycan biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in protein O-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi medial cisterna	IEA Inferred from Electronic Annotation more info
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: beta-1,3-galactosyltransferase 6

NP_001038690.1

EC 2.4.1.134

XP_005155714.1

EC 2.4.1.134

XP_073772178.1

EC 2.4.1.134

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.