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NHSL1 NHS like 1 [ Homo sapiens (human) ]

Gene ID: 57224, updated on 7-Oct-2018

Summary

Official Symbol
NHSL1provided by HGNC
Official Full Name
NHS like 1provided by HGNC
Primary source
HGNC:HGNC:21021
See related
Ensembl:ENSG00000135540 Vega:OTTHUMG00000016321
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf63
Expression
Broad expression in small intestine (RPKM 4.4), colon (RPKM 3.6) and 17 other tissues See more
Orthologs

Genomic context

See NHSL1 in Genome Data Viewer
Location:
6q24.1
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (138422043..138692616, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (138743180..138893726, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene MARCKS like 1 pseudogene 2 Neighboring gene small integral membrane protein 28 Neighboring gene heme binding protein 2 Neighboring gene microRNA 3145 Neighboring gene mitochondrial carrier 1 pseudogene Neighboring gene uncharacterized LOC441172 Neighboring gene GVQW motif containing 2 Neighboring gene coiled-coil domain containing 28A Neighboring gene epithelial cell transforming 2 like Neighboring gene C-C motif chemokine receptor like 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1357

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001144060.1NP_001137532.1  NHS-like protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001137532.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, uses a distinct start codon, and includes an alternate in-frame exon, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus and includes an alternate segment, compared to isoform 1.
    Source sequence(s)
    AL391669, AL591375
    Consensus CDS
    CCDS47487.1
    UniProtKB/Swiss-Prot
    Q5SYE7
    Related
    ENSP00000344672.5, OTTHUMP00000236390, ENST00000343505.9, OTTHUMT00000043701
    Conserved Domains (1) summary
    pfam15273
    Location:255889
    NHS; NHS-like
  2. NM_020464.1NP_065197.1  NHS-like protein 1 isoform 1

    See identical proteins and their annotated locations for NP_065197.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL391669, AL591375
    Consensus CDS
    CCDS55063.1
    UniProtKB/Swiss-Prot
    Q5SYE7
    Related
    ENSP00000394546.2, OTTHUMP00000017937, ENST00000427025.6, OTTHUMT00000043700
    Conserved Domains (1) summary
    pfam15273
    Location:259893
    NHS; NHS-like

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

    Range
    138422043..138692616 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011535976.1XP_011534278.1  NHS-like protein 1 isoform X13

    Conserved Domains (1) summary
    pfam15273
    Location:197831
    NHS; NHS-like
  2. XM_024446497.1XP_024302265.1  NHS-like protein 1 isoform X14

    Conserved Domains (2) summary
    pfam15273
    Location:96730
    NHS; NHS-like
    cl28033
    Location:9531354
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
  3. XM_017011086.2XP_016866575.1  NHS-like protein 1 isoform X1

    Conserved Domains (1) summary
    pfam15273
    Location:321955
    NHS; NHS-like
  4. XM_011535967.3XP_011534269.1  NHS-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011534269.1

    Conserved Domains (1) summary
    pfam15273
    Location:321955
    NHS; NHS-like
  5. XM_011535966.3XP_011534268.1  NHS-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011534268.1

    Conserved Domains (1) summary
    pfam15273
    Location:321955
    NHS; NHS-like
  6. XM_011535968.3XP_011534270.1  NHS-like protein 1 isoform X4

    Conserved Domains (1) summary
    pfam15273
    Location:277911
    NHS; NHS-like
  7. XM_005267062.5XP_005267119.1  NHS-like protein 1 isoform X2

    Conserved Domains (1) summary
    pfam15273
    Location:303937
    NHS; NHS-like
  8. XM_017011087.1XP_016866576.1  NHS-like protein 1 isoform X3

  9. XM_011535972.2XP_011534274.1  NHS-like protein 1 isoform X9

    Conserved Domains (1) summary
    pfam15273
    Location:259893
    NHS; NHS-like
  10. XM_017011089.1XP_016866578.1  NHS-like protein 1 isoform X12

  11. XM_011535969.2XP_011534271.1  NHS-like protein 1 isoform X5

    Conserved Domains (1) summary
    pfam15273
    Location:274908
    NHS; NHS-like
  12. XM_011535973.3XP_011534275.1  NHS-like protein 1 isoform X10

    Conserved Domains (1) summary
    pfam15273
    Location:256890
    NHS; NHS-like
  13. XM_011535970.2XP_011534272.1  NHS-like protein 1 isoform X6

    Conserved Domains (1) summary
    pfam15273
    Location:273907
    NHS; NHS-like
  14. XM_011535974.3XP_011534276.1  NHS-like protein 1 isoform X11

    Conserved Domains (1) summary
    pfam15273
    Location:256890
    NHS; NHS-like
  15. XM_011535971.2XP_011534273.1  NHS-like protein 1 isoform X8

    Conserved Domains (1) summary
    pfam15273
    Location:267901
    NHS; NHS-like
  16. XM_017011088.1XP_016866577.1  NHS-like protein 1 isoform X7

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