U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

phka1a phosphorylase kinase, alpha 1a (muscle) [ Danio rerio (zebrafish) ]

Gene ID: 572183, updated on 5-Jul-2025
Official Symbol
phka1aprovided by ZNC
Official Full Name
phosphorylase kinase, alpha 1a (muscle)provided by ZNC
Primary source
ZFIN:ZDB-GENE-031118-56
See related
Ensembl:ENSDARG00000105159 AllianceGenome:ZFIN:ZDB-GENE-031118-56
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
phka1; wu:fl37h01
Summary
Predicted to enable calmodulin binding activity. Predicted to be involved in glycogen metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in glycogen storage disease and glycogen storage disease IXd. Orthologous to human PHKA1 (phosphorylase kinase regulatory subunit alpha 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See phka1a in Genome Data Viewer
Location:
chromosome: 7
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 7 NC_133182.1 (53557546..53594970, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 7 NC_007118.7 (51712542..51749685, complement)

Chromosome 7 - NC_133182.1Genomic Context describing neighboring genes Neighboring gene Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 Neighboring gene histone deacetylase 8 Neighboring gene liver-expressed antimicrobial peptide 2 Neighboring gene bone morphogenetic protein 15

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. In vivo imaging of calcium dynamics in zebrafish hepatocytes. Pozo-Morales M, et al. Hepatology, 2023 Mar 1. PMID 35829917
  2. High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis. Thomas HR, et al. PLoS One, 2014. PMID 25503746, Free PMC Article
  3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
Names
phosphorylase kinase, alpha 1 (muscle)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133182.1 Reference GRCz12tu Primary Assembly

    Range
    53557546..53594970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_073907333.1 → XP_073763434.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z7W8

  2. XM_073907332.1 → XP_073763433.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X2

    UniProtKB/TrEMBL
    A0A8M3B4E0, E7F4R5

  3. XM_073907331.1 → XP_073763432.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1

    UniProtKB/TrEMBL
    A0A286YAZ5, A0A8M2BE02

  4. XM_073907334.1 → XP_073763435.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X4

  5. XM_017357095.3 → XP_017212584.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z7W8

  6. XM_009303454.4 → XP_009301729.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X2

    UniProtKB/TrEMBL
    A0A8M3B4E0, E7F4R5
    Related
    ENSDARP00000077625.5, ENSDART00000083190.7
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15

  7. XM_005166519.5 → XP_005166576.1  phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1

    UniProtKB/TrEMBL
    A0A286YAZ5, A0A8M2BE02
    Related
    ENSDARP00000144382.1, ENSDART00000175523.2
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials