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KIAA1191 KIAA1191 [ Homo sapiens (human) ]

Gene ID: 57179, updated on 1-Jun-2020

Summary

Official Symbol
KIAA1191provided by HGNC
Official Full Name
KIAA1191provided by HGNC
Primary source
HGNC:HGNC:29209
See related
Ensembl:ENSG00000122203
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
p33MONOX; p60MONOX
Expression
Ubiquitous expression in kidney (RPKM 91.5), ovary (RPKM 39.0) and 25 other tissues See more
Orthologs

Genomic context

See KIAA1191 in Genome Data Viewer
Location:
5q35.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (176346061..176361865, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (175773065..175788809, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986487 Neighboring gene centrosomal protein 192kDa pseudogene Neighboring gene SUMO interacting motifs containing 1 Neighboring gene BRCA1/BRCA2-containing complex subunit 3 pseudogene 1 Neighboring gene microRNA 1271 Neighboring gene ADP ribosylation factor like GTPase 10 Neighboring gene NOP16 nucleolar protein Neighboring gene HIG1 hypoxia inducible domain family member 2A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21022, KIAA1191

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
putative monooxygenase p33MONOX
Names
brain-derived rescue factor p60MONOX
flavin monooxygenase motif-containing protein of 33 kDa
flavine monooxygenase motif-containing protein of 33 kDa
p60MONOX brain-derived rescue factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079684.2NP_001073152.1  putative monooxygenase p33MONOX isoform b

    See identical proteins and their annotated locations for NP_001073152.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks part of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Both variants 2 and 5 encode the same isoform.
    Source sequence(s)
    AA569811, AL037719, AL390217, BC017097, HY119081
    Consensus CDS
    CCDS43402.1
    UniProtKB/Swiss-Prot
    Q96A73
    Related
    ENSP00000377326.2, ENST00000393725.6
    Conserved Domains (1) summary
    pfam15302
    Location:1286
    P33MONOX; P33 mono-oxygenase
  2. NM_001079685.2NP_001073153.1  putative monooxygenase p33MONOX isoform a

    See identical proteins and their annotated locations for NP_001073153.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Both variants 1 and 3 encode the same isoform (a).
    Source sequence(s)
    AA569811, AL037719, BC017097, DA789543, HY119081
    Consensus CDS
    CCDS4399.1
    UniProtKB/Swiss-Prot
    Q96A73
    UniProtKB/TrEMBL
    A0A024R7Q7
    Related
    ENSP00000421061.1, ENST00000510164.5
    Conserved Domains (1) summary
    pfam15302
    Location:17305
    P33MONOX; P33 mono-oxygenase
  3. NM_001287335.1NP_001274264.1  putative monooxygenase p33MONOX isoform c

    See identical proteins and their annotated locations for NP_001274264.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks part of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AA569811, AL037719, BX648859, HY114499, HY119081
    Consensus CDS
    CCDS75373.1
    UniProtKB/Swiss-Prot
    Q96A73
    UniProtKB/TrEMBL
    A0A087WT18
    Related
    ENSP00000477518.1, ENST00000620366.4
    Conserved Domains (1) summary
    pfam15302
    Location:2224
    P33MONOX; P33 mono-oxygenase
  4. NM_001287336.1NP_001274265.1  putative monooxygenase p33MONOX isoform b

    See identical proteins and their annotated locations for NP_001274265.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks part of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Both variants 2 and 5 encode the same isoform.
    Source sequence(s)
    AA569811, AL037719, BX648859, HY119081
    Consensus CDS
    CCDS43402.1
    UniProtKB/Swiss-Prot
    Q96A73
    Related
    ENSP00000479627.1, ENST00000614420.4
    Conserved Domains (1) summary
    pfam15302
    Location:1286
    P33MONOX; P33 mono-oxygenase
  5. NM_020444.5NP_065177.2  putative monooxygenase p33MONOX isoform a

    See identical proteins and their annotated locations for NP_065177.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Both variants 1 and 3 encode the same isoform.
    Source sequence(s)
    AA569811, BX648859
    Consensus CDS
    CCDS4399.1
    UniProtKB/Swiss-Prot
    Q96A73
    UniProtKB/TrEMBL
    A0A024R7Q7
    Related
    ENSP00000298569.4, ENST00000298569.9
    Conserved Domains (1) summary
    pfam15302
    Location:17305
    P33MONOX; P33 mono-oxygenase

RNA

  1. NR_109796.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks several consecutive internal exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AA569811, AL037719, BX648859, HY119081, HY120613
  2. NR_109797.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks several internal exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AA569811, AL037719, BM547296, BX648859, HY119081
  3. NR_109798.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) lacks several internal exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AA569811, AL037719, BX648859, CN341192, HY119081
  4. NR_109799.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) lacks several internal exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AA569811, AL037719, BC012848, HY119081
  5. NR_109800.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) lacks several internal exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AA569811, AL037719, BC006316, HY119081
    Related
    ENST00000393728.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    176346061..176361865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009652.1XP_016865141.1  putative monooxygenase p33MONOX isoform X3

  2. XM_005265946.4XP_005266003.1  putative monooxygenase p33MONOX isoform X1

    See identical proteins and their annotated locations for XP_005266003.1

    UniProtKB/Swiss-Prot
    Q96A73
    Conserved Domains (1) summary
    pfam15302
    Location:1286
    P33MONOX; P33 mono-oxygenase
  3. XM_017009651.1XP_016865140.1  putative monooxygenase p33MONOX isoform X2

    UniProtKB/TrEMBL
    A0A087WT18
    Conserved Domains (1) summary
    pfam15302
    Location:2224
    P33MONOX; P33 mono-oxygenase
  4. XM_017009653.1XP_016865142.1  putative monooxygenase p33MONOX isoform X4

    Conserved Domains (1) summary
    pfam15302
    Location:11203
    P33MONOX; P33 mono-oxygenase
  5. XM_011534596.1XP_011532898.1  putative monooxygenase p33MONOX isoform X2

    See identical proteins and their annotated locations for XP_011532898.1

    UniProtKB/TrEMBL
    A0A087WT18
    Conserved Domains (1) summary
    pfam15302
    Location:2224
    P33MONOX; P33 mono-oxygenase
  6. XM_024446134.1XP_024301902.1  putative monooxygenase p33MONOX isoform X4

    Conserved Domains (1) summary
    pfam15302
    Location:11203
    P33MONOX; P33 mono-oxygenase
  7. XM_011534595.2XP_011532897.1  putative monooxygenase p33MONOX isoform X2

    See identical proteins and their annotated locations for XP_011532897.1

    UniProtKB/TrEMBL
    A0A087WT18
    Conserved Domains (1) summary
    pfam15302
    Location:2224
    P33MONOX; P33 mono-oxygenase
  8. XM_024446133.1XP_024301901.1  putative monooxygenase p33MONOX isoform X1

    Conserved Domains (1) summary
    pfam15302
    Location:1286
    P33MONOX; P33 mono-oxygenase
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