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SLC44A2 solute carrier family 44 member 2 [ Homo sapiens (human) ]

Gene ID: 57153, updated on 21-Dec-2019

Summary

Official Symbol
SLC44A2provided by HGNC
Official Full Name
solute carrier family 44 member 2provided by HGNC
Primary source
HGNC:HGNC:17292
See related
Ensembl:ENSG00000129353 MIM:606106
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CTL2; PP1292
Expression
Ubiquitous expression in placenta (RPKM 82.0), spleen (RPKM 69.3) and 25 other tissues See more
Orthologs

Genomic context

See SLC44A2 in Genome Data Viewer
Location:
19p13.2
Exon count:
24
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (10602455..10644557)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (10713121..10755235)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 1 subunit mu 2 Neighboring gene LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) pseudogene Neighboring gene ILF3 divergent transcript Neighboring gene interleukin enhancer binding factor 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ44586, DKFZp666A071

Gene Ontology Provided by GOA

Function Evidence Code Pubs
choline transmembrane transporter activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
integral component of membrane TAS
Traceable Author Statement
more info
PubMed 
lysosomal membrane HDA PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
specific granule membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
choline transporter-like protein 2
Names
solute carrier family 44 (choline transporter), member 2
testicular tissue protein Li 47

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145056.2NP_001138528.1  choline transporter-like protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001138528.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region compared to variant 1. The encoded isoform (2) has a shorter, distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC011475, AK027519, BI602883, DA628435
    Consensus CDS
    CCDS54216.1
    UniProtKB/Swiss-Prot
    Q8IWA5
    UniProtKB/TrEMBL
    A0A088QCU6
    Related
    ENSP00000385135.3, ENST00000407327.8
    Conserved Domains (1) summary
    pfam04515
    Location:335673
    Choline_transpo; Plasma-membrane choline transporter
  2. NM_001363611.2NP_001350540.1  choline transporter-like protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC011475, AU310140, BC040556, DA673268, DA749803, HY323543
    Consensus CDS
    CCDS86700.1
    Related
    ENSP00000466664.1, ENST00000586078.5
    Conserved Domains (1) summary
    pfam04515
    Location:337675
    Choline_transpo; Plasma-membrane choline transporter
  3. NM_020428.4NP_065161.3  choline transporter-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_065161.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant encodes isoform 1.
    Source sequence(s)
    AC011475, BC040556, DA673268, DA749803
    Consensus CDS
    CCDS12245.1
    UniProtKB/Swiss-Prot
    Q8IWA5
    Related
    ENSP00000336888.4, ENST00000335757.10
    Conserved Domains (1) summary
    pfam04515
    Location:337675
    Choline_transpo; Plasma-membrane choline transporter

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    10602455..10644557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005259999.2XP_005260056.1  choline transporter-like protein 2 isoform X2

    Conserved Domains (1) summary
    pfam04515
    Location:335673
    Choline_transpo; Plasma-membrane choline transporter
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