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PLXDC1 plexin domain containing 1 [ Homo sapiens (human) ]

Gene ID: 57125, updated on 21-Dec-2019

Summary

Official Symbol
PLXDC1provided by HGNC
Official Full Name
plexin domain containing 1provided by HGNC
Primary source
HGNC:HGNC:20945
See related
Ensembl:ENSG00000161381 MIM:606826
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TEM3; TEM7
Expression
Ubiquitous expression in gall bladder (RPKM 7.4), endometrium (RPKM 6.4) and 23 other tissues See more
Orthologs

Genomic context

See PLXDC1 in Genome Data Viewer
Location:
17q12
Exon count:
14
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (39063313..39151637, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (37219556..37308946, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371767 Neighboring gene long intergenic non-protein coding RNA 2079 Neighboring gene leucine rich repeat containing 37 member A11, pseudogene Neighboring gene RDM1 pseudogene 5 Neighboring gene tRNA-Cys (anticodon GCA) 2-3 Neighboring gene tRNA-Cys (anticodon GCA) 2-4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36270, FLJ45632, DKFZp686F0937

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
angiogenesis NAS
Non-traceable Author Statement
more info
PubMed 
spinal cord development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
dendrite IEA
Inferred from Electronic Annotation
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
receptor complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
plexin domain-containing protein 1
Names
2410003I07Rik
tumor endothelial marker 3
tumor endothelial marker 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020405.5NP_065138.2  plexin domain-containing protein 1 precursor

    See identical proteins and their annotated locations for NP_065138.2

    Status: VALIDATED

    Source sequence(s)
    AC091178, AF378753, AK312999, BC036059, DA205327
    Consensus CDS
    CCDS11333.1
    UniProtKB/Swiss-Prot
    Q8IUK5
    Related
    ENSP00000323927.4, ENST00000315392.9
    Conserved Domains (3) summary
    pfam01437
    Location:303347
    PSI; Plexin repeat
    pfam05283
    Location:303441
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
    cl02648
    Location:152242
    NIDO; Nidogen-like

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    39063313..39151637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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