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PLAAT1 phospholipase A and acyltransferase 1 [ Homo sapiens (human) ]

Gene ID: 57110, updated on 21-Dec-2019

Summary

Official Symbol
PLAAT1provided by HGNC
Official Full Name
phospholipase A and acyltransferase 1provided by HGNC
Primary source
HGNC:HGNC:14922
See related
Ensembl:ENSG00000127252 MIM:606487
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
A-C1; HRSL1; HSD28; HRASLS; HRASLS1; PLA/AT1; PLAAT-1; H-REV107
Expression
Biased expression in testis (RPKM 17.3), thyroid (RPKM 1.8) and 3 other tissues See more
Orthologs

Genomic context

See PLAAT1 in Genome Data Viewer
Location:
3q29
Exon count:
8
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (193241128..193281639)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (192948030..193025102)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene vascular endothelial zinc finger 1 pseudogene 1 Neighboring gene uncharacterized LOC105374280 Neighboring gene uncharacterized protein MGC2889 Neighboring gene ATPase 13A5 Neighboring gene ATP13A5 antisense RNA 1 Neighboring gene ATPase 13A4 Neighboring gene ATP13A4 antisense RNA 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
N-acylphosphatidylethanolamine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
phosphatidylcholine metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear envelope lumen ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
phospholipase A and acyltransferase 1
Names
H-REV107 protein-related protein
HRAS like suppressor
HRAS-like suppressor 1
phospholipase A
phospholipase A/acyltransferase 1
phospholipid-metabolizing enzyme A-C1
NP_001353041.1
NP_065119.3
XP_011511336.1
XP_011511337.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366112.1NP_001353041.1  phospholipase A and acyltransferase 1

    Status: VALIDATED

    Source sequence(s)
    AC092966, AC105057
    Conserved Domains (1) summary
    pfam04970
    Location:26130
    LRAT; Lecithin retinol acyltransferase
  2. NM_020386.5NP_065119.3  phospholipase A and acyltransferase 1

    Status: VALIDATED

    Source sequence(s)
    BC048095, BX098792
    Consensus CDS
    CCDS3303.2
    Related
    ENSP00000264735.4, ENST00000264735.4
    Conserved Domains (1) summary
    pfam04970
    Location:26130
    LRAT; Lecithin retinol acyltransferase

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    193241128..193281639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011513035.2XP_011511337.1  phospholipase A and acyltransferase 1 isoform X2

    Conserved Domains (1) summary
    pfam04970
    Location:131235
    LRAT; Lecithin retinol acyltransferase
  2. XM_011513034.1XP_011511336.1  phospholipase A and acyltransferase 1 isoform X1

    Conserved Domains (1) summary
    pfam04970
    Location:131235
    LRAT; Lecithin retinol acyltransferase
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