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Gtf2ird1 general transcription factor II I repeat domain-containing 1 [ Mus musculus (house mouse) ]

Gene ID: 57080, updated on 17-Jul-2018
Official Symbol
Gtf2ird1provided by MGI
Official Full Name
general transcription factor II I repeat domain-containing 1provided by MGI
Primary source
MGI:MGI:1861942
See related
Ensembl:ENSMUSG00000023079 Vega:OTTMUSG00000055742
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BEN; GTF3; ESTM9; Cream1; Gtf2il; X83320; MusTRD1; WBSCR11; 1700012P16Rik; Tg(Alb1-Myc)166.8Sst
Expression
Ubiquitous expression in limb E14.5 (RPKM 16.4), CNS E11.5 (RPKM 13.0) and 28 other tissues See more
Orthologs
See Gtf2ird1 in Genome Data Viewer
Location:
5 G2; 5 74.55 cM
Exon count:
35
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (134357661..134456716, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (134833531..134932581, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 46925 Neighboring gene predicted gene 7033 Neighboring gene ribosomal protein S28 pseudogene Neighboring gene CAP-GLY domain containing linker protein 2

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Basal transcription factors, organism-specific biosystem (from KEGG)
    Basal transcription factors, organism-specific biosystem
    Basal transcription factors
  • Basal transcription factors, conserved biosystem (from KEGG)
    Basal transcription factors, conserved biosystem
    Basal transcription factors
  • Herpes simplex infection, organism-specific biosystem (from KEGG)
    Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Herpes simplex infection, conserved biosystem (from KEGG)
    Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • cGMP-PKG signaling pathway, organism-specific biosystem (from KEGG)
    cGMP-PKG signaling pathway, organism-specific biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...
  • cGMP-PKG signaling pathway, conserved biosystem (from KEGG)
    cGMP-PKG signaling pathway, conserved biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...

Markers

Homology

Clone Names

  • MGC102438

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transition between slow and fast fiber IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
general transcription factor II-I repeat domain-containing protein 1
Names
Alb/c-myc line 166.8
GTF2I repeat domain-containing 1
GTF2I repeat domain-containing protein 1
Williams-Beuren syndrome chromosome region 11
binding factor for early enhancer
c-myc line 166.8
general transcription factor 3
muscle TFII-I repeat domain-containing protein 1
transcription factor GTF3 alpha 2
transcription factor GTF3 gamma 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081462.2NP_001074931.1  general transcription factor II-I repeat domain-containing protein 1 isoform b

    See identical proteins and their annotated locations for NP_001074931.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (b) has a longer and distinct C-terminus, as compared to isoform a.
    Source sequence(s)
    AC167419, AF257475, AI413504, CJ178886
    Consensus CDS
    CCDS39307.1
    UniProtKB/Swiss-Prot
    Q9JI57
    Related
    ENSMUSP00000098217.3, OTTMUSP00000072572, ENSMUST00000100652.9, OTTMUST00000137922
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  2. NM_001081463.2NP_001074932.1  general transcription factor II-I repeat domain-containing protein 1 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (c) lacks an internal segment and has a longer and distinct C-terminus, as compared to isoform a.
    Source sequence(s)
    AC167419, AF343350, AI413504, AK078488, CJ178886
    Consensus CDS
    CCDS39306.1
    UniProtKB/Swiss-Prot
    Q9JI57
    UniProtKB/TrEMBL
    Q8BP10
    Related
    ENSMUSP00000098215.3, OTTMUSP00000072573, ENSMUST00000100650.9, OTTMUST00000137923
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  3. NM_001081464.2NP_001074933.1  general transcription factor II-I repeat domain-containing protein 1 isoform d

    See identical proteins and their annotated locations for NP_001074933.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, as compared to variant 1. The encoded isoform (d) lacks an internal segment, as compared to isoform a.
    Source sequence(s)
    BC050822, CJ178886
    Consensus CDS
    CCDS39304.1
    UniProtKB/TrEMBL
    Q6PD35
    Related
    ENSMUSP00000129392.2, OTTMUSP00000072562, ENSMUST00000171794.8, OTTMUST00000137912
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  4. NM_001081465.1NP_001074934.1  general transcription factor II-I repeat domain-containing protein 1 isoform d

    See identical proteins and their annotated locations for NP_001074934.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and lacks an in-frame coding exon, as compared to variant 1. The encoded isoform (d) lacks an internal segment, as compared to isoform a.
    Source sequence(s)
    AK078488, BC050822, BC083150, CJ048288
    Consensus CDS
    CCDS39304.1
    UniProtKB/TrEMBL
    Q5XJY7, Q6PD35, Q8BP10
    Related
    ENSMUSP00000106875.1, OTTMUSP00000072561, ENSMUST00000111244.4, OTTMUST00000137911
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  5. NM_001081466.2NP_001074935.1  general transcription factor II-I repeat domain-containing protein 1 isoform e

    See identical proteins and their annotated locations for NP_001074935.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two in-frame exons in the coding region, as compared to variant 1. The encoded isoform (e) lacks two segments, as compared to isoform a.
    Source sequence(s)
    AF343349, BC050822, CJ178886
    Consensus CDS
    CCDS39302.1
    UniProtKB/Swiss-Prot
    Q9JI57
    UniProtKB/TrEMBL
    Q6PD35
    Related
    ENSMUSP00000106876.2, OTTMUSP00000072568, ENSMUST00000111245.8, OTTMUST00000137918
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  6. NM_001081467.2NP_001074936.1  general transcription factor II-I repeat domain-containing protein 1 isoform f

    See identical proteins and their annotated locations for NP_001074936.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (f) lacks an internal segment and has a longer and distinct C-terminus, as compared to isoform a.
    Source sequence(s)
    AC167419, AF257475, AI413504, BC050822, CJ178886
    Consensus CDS
    CCDS51657.1
    UniProtKB/Swiss-Prot
    Q9JI57
    UniProtKB/TrEMBL
    Q6PD35
    Related
    ENSMUSP00000073752.5, OTTMUSP00000072570, ENSMUST00000074114.11, OTTMUST00000137920
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  7. NM_001081468.2NP_001074937.1  general transcription factor II-I repeat domain-containing protein 1 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) lacks three exons in the 3' coding region but maintains the reading frame, as compared to variant 1. The encoded isoform (g) lacks an internal segment, as compared to isoform a.
    Source sequence(s)
    BC050822, CJ178886
    Consensus CDS
    CCDS39303.1
    UniProtKB/TrEMBL
    Q6PD35
    Related
    ENSMUSP00000098219.3, OTTMUSP00000072567, ENSMUST00000100654.9, OTTMUST00000137917
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  8. NM_001081469.2NP_001074938.1  general transcription factor II-I repeat domain-containing protein 1 isoform h

    See identical proteins and their annotated locations for NP_001074938.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) lacks three exons in the 3' coding region but maintains the reading frame, as compared to variant 1. The encoded isoform (h) lacks an internal segment, as compared to isoform a.
    Source sequence(s)
    AF257475, BC050822, CJ178886
    Consensus CDS
    CCDS80420.1
    UniProtKB/Swiss-Prot
    Q9JI57
    UniProtKB/TrEMBL
    Q6PD35
    Related
    ENSMUSP00000143848.1, OTTMUSP00000072566, ENSMUST00000200944.3, OTTMUST00000137916
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  9. NM_001081470.2NP_001074939.1  general transcription factor II-I repeat domain-containing protein 1 isoform i

    See identical proteins and their annotated locations for NP_001074939.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) lacks four exons in the 3' coding region but maintains the reading frame, as compared to variant 1. The encoded isoform (i) lacks two internal segments, as compared to isoform a.
    Source sequence(s)
    BC050822, CJ178886
    UniProtKB/Swiss-Prot
    Q9JI57
    UniProtKB/TrEMBL
    Q6PD35
    Related
    ENSMUSP00000143897.1, OTTMUSP00000072565, ENSMUST00000202280.3, OTTMUST00000137915
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  10. NM_001244936.1NP_001231865.1  general transcription factor II-I repeat domain-containing protein 1 isoform j

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (j) lacks two internal segments and has a longer and distinct C-terminus, as compared to isoform a.
    Source sequence(s)
    AC167419, AF257475, AI413504, BC050822, CJ178886
    UniProtKB/Swiss-Prot
    Q9JI57
    UniProtKB/TrEMBL
    Q6PD35
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  11. NM_001347488.1NP_001334417.1  general transcription factor II-I repeat domain-containing protein 1 isoform k

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) lacks two in-frame exons and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (k) lacks two alternate internal segments and has a distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC167419
    Consensus CDS
    CCDS84967.1
    UniProtKB/Swiss-Prot
    Q9JI57
  12. NM_020331.3NP_065064.2  general transcription factor II-I repeat domain-containing protein 1 isoform a

    See identical proteins and their annotated locations for NP_065064.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the full-length transcript containing all exons of the gene. Variant 1 encodes isoform a.
    Source sequence(s)
    AF343348, BC050822, CJ178886
    Consensus CDS
    CCDS39305.1
    UniProtKB/Swiss-Prot
    Q9JI57
    UniProtKB/TrEMBL
    Q6PD35
    Related
    ENSMUSP00000072904.5, OTTMUSP00000072563, ENSMUST00000073161.11, OTTMUST00000137913
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    134357661..134456716 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017321047.1XP_017176536.1  general transcription factor II-I repeat domain-containing protein 1 isoform X22

  2. XM_017321046.1XP_017176535.1  general transcription factor II-I repeat domain-containing protein 1 isoform X21

  3. XM_017321044.1XP_017176533.1  general transcription factor II-I repeat domain-containing protein 1 isoform X19

  4. XM_006504466.2XP_006504529.1  general transcription factor II-I repeat domain-containing protein 1 isoform X11

    Related
    ENSMUSP00000143809.1, OTTMUSP00000072571, ENSMUST00000202554.3, OTTMUST00000137921
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  5. XM_017321045.1XP_017176534.1  general transcription factor II-I repeat domain-containing protein 1 isoform X20

  6. XM_017321042.1XP_017176531.1  general transcription factor II-I repeat domain-containing protein 1 isoform X17

  7. XM_006504462.2XP_006504525.1  general transcription factor II-I repeat domain-containing protein 1 isoform X8

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  8. XM_017321043.1XP_017176532.1  general transcription factor II-I repeat domain-containing protein 1 isoform X18

  9. XM_017321040.1XP_017176529.1  general transcription factor II-I repeat domain-containing protein 1 isoform X13

  10. XM_011240895.1XP_011239197.1  general transcription factor II-I repeat domain-containing protein 1 isoform X9

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  11. XM_011240891.1XP_011239193.1  general transcription factor II-I repeat domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  12. XM_017321041.1XP_017176530.1  general transcription factor II-I repeat domain-containing protein 1 isoform X15

  13. XM_011240894.1XP_011239196.1  general transcription factor II-I repeat domain-containing protein 1 isoform X7

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  14. XM_011240890.1XP_011239192.1  general transcription factor II-I repeat domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  15. XM_011240897.1XP_011239199.1  general transcription factor II-I repeat domain-containing protein 1 isoform X14

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  16. XM_011240896.1XP_011239198.1  general transcription factor II-I repeat domain-containing protein 1 isoform X12

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  17. XM_011240893.1XP_011239195.1  general transcription factor II-I repeat domain-containing protein 1 isoform X6

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  18. XM_011240892.1XP_011239194.1  general transcription factor II-I repeat domain-containing protein 1 isoform X4

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  19. XM_011240885.1XP_011239187.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011239187.1

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  20. XM_011240900.1XP_011239202.1  general transcription factor II-I repeat domain-containing protein 1 isoform X23

    Conserved Domains (1) summary
    pfam02946
    Location:349421
    GTF2I; GTF2I-like repeat
  21. XM_011240886.2XP_011239188.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011239188.1

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  22. XM_017321039.1XP_017176528.1  general transcription factor II-I repeat domain-containing protein 1 isoform X10

    UniProtKB/Swiss-Prot
    Q9JI57
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  23. XM_017321038.1XP_017176527.1  general transcription factor II-I repeat domain-containing protein 1 isoform X5

    UniProtKB/Swiss-Prot
    Q9JI57
    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  24. XM_011240889.1XP_011239191.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011239191.1

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  25. XM_011240901.2XP_011239203.1  general transcription factor II-I repeat domain-containing protein 1 isoform X24

    Conserved Domains (1) summary
    pfam02946
    Location:270342
    GTF2I; GTF2I-like repeat
  26. XM_011240888.2XP_011239190.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011239190.1

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  27. XM_011240887.2XP_011239189.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011239189.1

    Conserved Domains (1) summary
    pfam02946
    Location:565637
    GTF2I; GTF2I-like repeat
  28. XM_011240898.1XP_011239200.1  general transcription factor II-I repeat domain-containing protein 1 isoform X16

    Conserved Domains (1) summary
    pfam02946
    Location:422494
    GTF2I; GTF2I-like repeat
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