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thrap3a thyroid hormone receptor associated protein 3a [ Danio rerio (zebrafish) ]

Gene ID: 570454, updated on 27-Mar-2024

Summary

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Official Symbol
thrap3aprovided by ZNC
Official Full Name
thyroid hormone receptor associated protein 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030219-79
See related
Ensembl:ENSDARG00000101989 AllianceGenome:ZFIN:ZDB-GENE-030219-79
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
id:ibd5132; si:dkeyp-114b5.3
Summary
Predicted to enable DNA binding activity and transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within RNA splicing. Predicted to be part of mediator complex. Is expressed in primitive heart tube and somite. Orthologous to human THRAP3 (thyroid hormone receptor associated protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 16
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (35870468..35903439)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (35917616..35950572)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene si:ch211-1i11.3 Neighboring gene MAP7 domain containing 1a Neighboring gene SH3 domain containing 21 Neighboring gene eva-1 homolog Ba (C. elegans)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
thyroid hormone receptor-associated protein 3
Names
thyroid hormone receptor associated protein 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    35870468..35903439
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466955.1 → XP_021322630.1  thyroid hormone receptor-associated protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8M9PN52
    Related
    ENSDARP00000134639.1, ENSDART00000169677.2
    Conserved Domains (1) summary
    pfam15440
    Location:501 → 688
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

  2. XM_009292517.3 → XP_009290792.1  thyroid hormone receptor-associated protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AIC8
    Conserved Domains (1) summary
    pfam15440
    Location:137 → 736
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

  3. XM_021466954.1 → XP_021322629.1  thyroid hormone receptor-associated protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A2R8RHG4, A0A8M3AQV5
    Conserved Domains (1) summary
    pfam15440
    Location:501 → 736
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

  4. XM_009292516.3 → XP_009290791.1  thyroid hormone receptor-associated protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A2R8RHG4, A0A8M3AQV5
    Related
    ENSDARP00000144710.1, ENSDART00000184321.1
    Conserved Domains (1) summary
    pfam15440
    Location:501 → 736
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

  5. XM_009292518.3 → XP_009290793.1  thyroid hormone receptor-associated protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A0R4IWK3, A0A8M3B1W3
    Related
    ENSDARP00000139100.2, ENSDART00000170772.2
    Conserved Domains (1) summary
    pfam15440
    Location:97 → 696
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
Nucleotide Protein Strain
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