aqp9b aquaporin 9b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aqp9bprovided by ZNC
Official Full Name: aquaporin 9bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070911-1
See related: Ensembl:ENSDARG00000053480 AllianceGenome:ZFIN:ZDB-GENE-070911-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: aqp9
Summary: Enables several functions, including arsenite transmembrane transporter activity; glycerol transmembrane transporter activity; and water transmembrane transporter activity. Predicted to be involved in glycerol transmembrane transport and water transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be active in basolateral plasma membrane. Is expressed in several structures, including eye; gill; liver; muscle; and ovary. Orthologous to human AQP9 (aquaporin 9). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	7	NC_133182.1 (30349089..30365665)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (30371893..30388779)

Chromosome 7 - NC_133182.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables arsenite transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables channel activity	IEA Inferred from Electronic Annotation more info
enables glycerol channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycerol transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables urea transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables urea transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables water channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables water transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in glycerol transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in water transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in basolateral plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: aquaporin-9b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177744.1 → NP_001171215.1 aquaporin-9b

See identical proteins and their annotated locations for NP_001171215.1

Status: PROVISIONAL

Source sequence(s)

EU341835

UniProtKB/TrEMBL

A0AB32TV43, D5FFZ1

Related

ENSDARP00000069995.5, ENSDART00000075513.7

Conserved Domains (1) summary

cd00333
Location:22 → 228

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...