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SDHAF3 succinate dehydrogenase complex assembly factor 3 [ Homo sapiens (human) ]

Gene ID: 57001, updated on 11-Sep-2019

Summary

Official Symbol
SDHAF3provided by HGNC
Official Full Name
succinate dehydrogenase complex assembly factor 3provided by HGNC
Primary source
HGNC:HGNC:21752
See related
Ensembl:ENSG00000196636 MIM:615773
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ACN9; DC11; Sdh7; LYRM10
Expression
Ubiquitous expression in kidney (RPKM 6.5), testis (RPKM 5.6) and 25 other tissues See more
Orthologs

Genomic context

See SDHAF3 in Genome Data Viewer
Location:
7q21.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (97117698..97181763)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (96745905..96811075)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene DLX6 antisense RNA 1 Neighboring gene distal-less homeobox 6 Neighboring gene distal-less homeobox 5 Neighboring gene uncharacterized LOC107984034 Neighboring gene high mobility group box 3 pseudogene 21 Neighboring gene uncharacterized LOC105375417 Neighboring gene ribosomal protein L7a pseudogene 40 Neighboring gene uncharacterized LOC107986826

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
mitochondrial respiratory chain complex II assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of gluconeogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
succinate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial intermembrane space ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
succinate dehydrogenase assembly factor 3, mitochondrial
Names
ACN9 homolog
SDH assembly factor 3
protein ACN9 homolog, mitochondrial

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020186.3NP_064571.1  succinate dehydrogenase assembly factor 3, mitochondrial precursor

    See identical proteins and their annotated locations for NP_064571.1

    Status: VALIDATED

    Source sequence(s)
    AC073421, AC073900
    Consensus CDS
    CCDS5648.1
    UniProtKB/Swiss-Prot
    Q9NRP4
    Related
    ENSP00000414066.2, ENST00000432641.2
    Conserved Domains (1) summary
    pfam13233
    Location:973
    Complex1_LYR_2; Complex1_LYR-like

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    97117698..97181763
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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