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dvl1a dishevelled segment polarity protein 1a [ Danio rerio (zebrafish) ]

Gene ID: 569863, updated on 1-Aug-2018

Summary

Official Symbol
dvl1aprovided by ZNC
Official Full Name
dishevelled segment polarity protein 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090312-40
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
si:dkey-223i19.4
Orthologs

Genomic context

See dvl1a in Genome Data Viewer
Location:
chromosome: 23
Exon count:
16
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (29908009..29992835)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (29981479..30066202)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene aurora kinase A interacting protein 1 Neighboring gene matrix-remodelling associated 8b Neighboring gene tumor necrosis factor receptor superfamily, member 9a Neighboring gene coiled-coil domain containing 187

Genomic regions, transcripts, and products

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General protein information

Preferred Names
dishevelled segment polarity protein 1a; segment polarity protein dishevelled homolog DVL-1
Names
dishevelled, dsh homolog 1a

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    29908009..29992835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470001.1XP_021325676.1  segment polarity protein dishevelled homolog DVL-1 isoform X7

    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:254348
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:404487
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90252
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:491563
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  2. XM_021470000.1XP_021325675.1  segment polarity protein dishevelled homolog DVL-1 isoform X3

    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252346
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:402485
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:489726
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  3. XM_021469998.1XP_021325673.1  segment polarity protein dishevelled homolog DVL-1 isoform X1

    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:254348
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:404487
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90252
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:491728
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  4. XM_017353751.2XP_017209240.1  segment polarity protein dishevelled homolog DVL-1 isoform X4

  5. XM_021469999.1XP_021325674.1  segment polarity protein dishevelled homolog DVL-1 isoform X2

    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252346
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:402485
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:489726
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  6. XM_017353754.2XP_017209243.1  segment polarity protein dishevelled homolog DVL-1 isoform X6

  7. XM_017353752.2XP_017209241.1  segment polarity protein dishevelled homolog DVL-1 isoform X5

    UniProtKB/TrEMBL
    E7FAJ8

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395157.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    1323..20341
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473719.1XP_021329394.1  segment polarity protein dishevelled homolog DVL-1 isoform X8

    Conserved Domains (3) summary
    cd00992
    Location:1993
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:149232
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam12316
    Location:236473
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
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