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CEACAM19 CEA cell adhesion molecule 19 [ Homo sapiens (human) ]

Gene ID: 56971, updated on 26-Oct-2022

Summary

Official Symbol
CEACAM19provided by HGNC
Official Full Name
CEA cell adhesion molecule 19provided by HGNC
Primary source
HGNC:HGNC:31951
See related
Ensembl:ENSG00000186567 MIM:606691; AllianceGenome:HGNC:31951
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CEAL1; CEACM19
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in skin (RPKM 5.4), testis (RPKM 2.3) and 24 other tissues See more
Orthologs
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Genomic context

See CEACAM19 in Genome Data Viewer
Location:
19q13.31
Exon count:
9
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (44665860..44684355)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (47490642..47509104)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (45169128..45187627)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene immunoglobulin superfamily member 23 Neighboring gene Sharpr-MPRA regulatory region 2639 Neighboring gene PVR cell adhesion molecule Neighboring gene microRNA 4531 Neighboring gene uncharacterized LOC107985306 Neighboring gene Sharpr-MPRA regulatory region 3873 Neighboring gene CEA cell adhesion molecule 16, tectorial membrane component

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC105097

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 19
Names
carcinoembryonic antigen related cell adhesion molecule 19
carcinoembryonic antigen-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127893.3NP_001121365.1  carcinoembryonic antigen-related cell adhesion molecule 19 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001121365.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the shorter protein (isoform 1).
    Source sequence(s)
    AC243964
    Consensus CDS
    CCDS46108.1
    UniProtKB/Swiss-Prot
    Q7Z692
    Related
    ENSP00000351627.4, ENST00000358777.10
    Conserved Domains (2) summary
    cd00096
    Location:4244
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:36140
    Ig; Immunoglobulin domain
  2. NM_001389722.1NP_001376651.1  carcinoembryonic antigen-related cell adhesion molecule 19 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC243964
    Consensus CDS
    CCDS46108.1
    Conserved Domains (2) summary
    cd00096
    Location:4244
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:36140
    Ig; Immunoglobulin domain
  3. NM_020219.5NP_064604.2  carcinoembryonic antigen-related cell adhesion molecule 19 isoform 2 precursor

    See identical proteins and their annotated locations for NP_064604.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is longer and has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    AC243964
    Consensus CDS
    CCDS12641.1
    UniProtKB/Swiss-Prot
    Q7Z692, Q7Z693
    Related
    ENSP00000384887.3, ENST00000403660.3
    Conserved Domains (1) summary
    cl11960
    Location:36140
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    44665860..44684355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    47490642..47509104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)