U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

phkb phosphorylase kinase, beta [ Danio rerio (zebrafish) ]

Gene ID: 569706, updated on 5-Jul-2025
Official Symbol
phkbprovided by ZNC
Official Full Name
phosphorylase kinase, betaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-110411-149
See related
Ensembl:ENSDARG00000078284 AllianceGenome:ZFIN:ZDB-GENE-110411-149
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-96k10.1
Summary
Predicted to enable calmodulin binding activity. Predicted to be involved in glycogen metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in plasma membrane. Predicted to be part of phosphorylase kinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease IXb. Orthologous to human PHKB (phosphorylase kinase regulatory subunit beta). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See phkb in Genome Data Viewer
Location:
chromosome: 7
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 7 NC_133182.1 (42724081..42862714)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 7 NC_007118.7 (42206831..42345295)

Chromosome 7 - NC_133182.1Genomic Context describing neighboring genes Neighboring gene neuropilin (NRP) and tolloid (TLL)-like 2a Neighboring gene integrin alpha FG-GAP repeat containing 1 Neighboring gene uncharacterized LOC137490297 Neighboring gene G-protein coupled receptor 15-like Neighboring gene si:ch211-262h13.4 Neighboring gene uncharacterized LOC141375427

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Patterns of alternative splicing in response to cold acclimation in fish. Healy TM, et al. J Exp Biol, 2019 Mar 7. PMID 30692167
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of phosphorylase kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
phosphorylase b kinase regulatory subunit beta

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133182.1 Reference GRCz12tu Primary Assembly

    Range
    42724081..42862714
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_073908869.1 → XP_073764970.1  phosphorylase b kinase regulatory subunit beta isoform X4

  2. XM_693105.10 → XP_698197.5  phosphorylase b kinase regulatory subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A8N7UTG1, F8W2U7
    Related
    ENSDARP00000124602.2
    Conserved Domains (1) summary
    pfam00723
    Location:41 → 462
    Glyco_hydro_15; Glycosyl hydrolases family 15

  3. XM_005166403.6 → XP_005166460.1  phosphorylase b kinase regulatory subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A8M2BDU6
    Conserved Domains (1) summary
    pfam00723
    Location:44 → 465
    Glyco_hydro_15; Glycosyl hydrolases family 15

  4. XM_005166402.6 → XP_005166459.1  phosphorylase b kinase regulatory subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8M2BDW3, F1Q6F0
    Related
    ENSDARP00000103850.3
    Conserved Domains (1) summary
    pfam00723
    Location:44 → 465
    Glyco_hydro_15; Glycosyl hydrolases family 15
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools