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ints6 integrator complex subunit 6 [ Danio rerio (zebrafish) ]

Gene ID: 569456, updated on 9-Sep-2025
Official Symbol
ints6provided by ZNC
Official Full Name
integrator complex subunit 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-070906-1
See related
Ensembl:ENSDARG00000013025 AllianceGenome:ZFIN:ZDB-GENE-070906-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ddx26a
Summary
Orthologous to human INTS6 (integrator complex subunit 6). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
human mouse all
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See ints6 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 9 NC_133184.1 (25444641..25460906)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 9 NC_007120.7 (23825440..23841704)

Chromosome 9 - NC_133184.1Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase (SDR family) member 12 Neighboring gene WD repeat and FYVE domain containing 2 Neighboring gene serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 Neighboring gene uncharacterized LOC141376126 Neighboring gene family with sequence similarity 124 member A

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. The integrator complex subunit 6 (Ints6) confines the dorsal organizer in vertebrate embryogenesis. Kapp LD, et al. PLoS Genet, 2013 Oct. PMID 24204286, Free PMC Article
  2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Our results are consistent with a novel role for Ints6 in restricting the vertebrate organizer to a dorsal domain in embryonic patterning.
    Title: The integrator complex subunit 6 (Ints6) confines the dorsal organizer in vertebrate embryogenesis.
Submit: New GeneRIF Correction

Homology

Preferred Names
integrator complex subunit 6
Names
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126428.1 → NP_001119900.1  integrator complex subunit 6

    See identical proteins and their annotated locations for NP_001119900.1

    Status: PROVISIONAL

    Source sequence(s)
    JBMGRA010000009
    UniProtKB/TrEMBL
    B0UYL7, V5LEJ6
    Related
    ENSDARP00000113971.1, ENSDART00000138470.2
    Conserved Domains (2) summary
    cd00198
    Location:4 → 131
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam15300
    Location:775 → 835
    INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133184.1 Reference GRCz12tu Primary Assembly

    Range
    25444641..25460906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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