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CCDC177 coiled-coil domain containing 177 [ Homo sapiens (human) ]

Gene ID: 56936, updated on 27-Nov-2024

Summary

Official Symbol
CCDC177provided by HGNC
Official Full Name
coiled-coil domain containing 177provided by HGNC
Primary source
HGNC:HGNC:23243
See related
Ensembl:ENSG00000267909 AllianceGenome:HGNC:23243
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PLPL; C14orf162
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See CCDC177 in Genome Data Viewer
Location:
14q24.1
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (69569799..69574871, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (63777470..63782536, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (70036516..70041588, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene pleckstrin homology and coiled-coil domain containing D1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_36437 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:70014029-70014585 Neighboring gene RPL24 pseudogene 3 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:70061623-70061793 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5882 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8639 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:70088656-70089156 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8640 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8641 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8642 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:70104475-70104987 Neighboring gene sushi domain containing 6 Neighboring gene Sharpr-MPRA regulatory region 10837 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:70124416-70125196 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8643 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8644 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8645 Neighboring gene Sharpr-MPRA regulatory region 2331 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8646 Neighboring gene Sharpr-MPRA regulatory region 930 Neighboring gene Sharpr-MPRA regulatory region 8327 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr14:70207027-70208226 Neighboring gene uncharacterized LOC100289511 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8647 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8648 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:70233975-70234739 Neighboring gene serine and arginine rich splicing factor 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
coiled-coil domain-containing protein 177
Names
myelin proteolipid protein-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271507.2NP_001258436.1  coiled-coil domain-containing protein 177

    See identical proteins and their annotated locations for NP_001258436.1

    Status: VALIDATED

    Source sequence(s)
    AL133445
    Consensus CDS
    CCDS59245.1
    UniProtKB/Swiss-Prot
    B2R5G1, Q2M359, Q9NQR7
    Related
    ENSP00000469474.1, ENST00000599174.3
    Conserved Domains (1) summary
    pfam15558
    Location:333706
    DUF4659; Domain of unknown function (DUF4659)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    69569799..69574871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    63777470..63782536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_020181.2: Suppressed sequence

    Description
    NM_020181.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
  2. NR_024630.1: Suppressed sequence

    Description
    NR_024630.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.