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mark4a MAP/microtubule affinity-regulating kinase 4a [ Danio rerio (zebrafish) ]

Gene ID: 569346, updated on 3-Oct-2019

Summary

Official Symbol
mark4aprovided by ZNC
Official Full Name
MAP/microtubule affinity-regulating kinase 4aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060531-156
See related
Ensembl:ENSDARG00000023914
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
sb:eu746; si:dkey-85k8.8

Genomic context

See mark4a in Genome Data Viewer
Location:
chromosome: 5
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (36781086..36824103)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (36180962..36222993)
103 previous assembly Zv9 (GCF_000002035.4) 5 NC_007116.5 (38381294..38424239)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14Aa Neighboring gene exocyst complex component 3-like 2a Neighboring gene uncharacterized LOC110438658 Neighboring gene creatine kinase, muscle a

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
tau-protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase 4a
XP_005165424.1
XP_005165425.1
XP_005165426.1
XP_021332218.1
XP_021332219.1
XP_021332220.1
XP_021332221.1
XP_697818.6

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    36781086..36824103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476543.1XP_021332218.1  MAP/microtubule affinity-regulating kinase 4 isoform X1

    Conserved Domains (3) summary
    cd12197
    Location:662762
    MARK4_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 4
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
  2. XM_021476544.1XP_021332219.1  MAP/microtubule affinity-regulating kinase 4 isoform X2

    Related
    ENSDARP00000121243.1, ENSDART00000146854.3
    Conserved Domains (3) summary
    cd12197
    Location:658758
    MARK4_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 4
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
  3. XM_021476545.1XP_021332220.1  MAP/microtubule affinity-regulating kinase 4 isoform X3

    Conserved Domains (2) summary
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
  4. XM_021476546.1XP_021332221.1  MAP/microtubule affinity-regulating kinase 4 isoform X4

    Conserved Domains (2) summary
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394595.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    22101..65118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005165367.4XP_005165424.1  MAP/microtubule affinity-regulating kinase 4 isoform X1

    UniProtKB/TrEMBL
    F1Q5N2
    Conserved Domains (3) summary
    cd12197
    Location:662762
    MARK4_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 4
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
  2. XM_005165368.4XP_005165425.1  MAP/microtubule affinity-regulating kinase 4 isoform X2

    Conserved Domains (3) summary
    cd12197
    Location:658758
    MARK4_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 4
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
  3. XM_005165369.4XP_005165426.1  MAP/microtubule affinity-regulating kinase 4 isoform X3

    Conserved Domains (2) summary
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
  4. XM_692726.9XP_697818.6  MAP/microtubule affinity-regulating kinase 4 isoform X4

    Conserved Domains (2) summary
    cd14407
    Location:327369
    UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
    cd14072
    Location:57309
    STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
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