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kmt5c lysine methyltransferase 5C [ Danio rerio (zebrafish) ]

Gene ID: 569041, updated on 11-Apr-2024

Summary

Official Symbol
kmt5cprovided by ZNC
Official Full Name
lysine methyltransferase 5Cprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080523-2
See related
Ensembl:ENSDARG00000075461 AllianceGenome:ZFIN:ZDB-GENE-080523-2
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
suv420h2; zgc:162876
Summary
Predicted to enable histone methyltransferase activity (H4-K20 specific). Acts upstream of or within histone H4-K20 methylation and regulation of growth. Predicted to be located in chromosome. Predicted to be active in nucleus. Orthologous to human KMT5C (lysine methyltransferase 5C). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (30873084..30888415, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (30742242..30757573, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene si:dkey-105i19.5 Neighboring gene SH3 and multiple ankyrin repeat domains 1 Neighboring gene protein phosphatase 1, catalytic subunit, alpha isozyme a Neighboring gene claudin i Neighboring gene coronin, actin binding protein, 1A

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC162876

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables histone H4K20 methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone H4K20 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables histone H4K20 methyltransferase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables histone H4K20 monomethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables histone H4K20me methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of multicellular organism growth IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
histone-lysine N-methyltransferase KMT5C
Names
suppressor of variegation 4-20 homolog 2
suppressor of variegation 4-20 protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098186.2NP_001091656.2  histone-lysine N-methyltransferase KMT5C

    Status: VALIDATED

    Source sequence(s)
    BX682556
    Related
    ENSDARP00000106462.1, ENSDART00000124458.2

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    30873084..30888415 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394533.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    463013..478344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)