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ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B [ Homo sapiens (human) ]

Gene ID: 56899, updated on 5-Aug-2018

Summary

Official Symbol
ANKS1Bprovided by HGNC
Official Full Name
ankyrin repeat and sterile alpha motif domain containing 1Bprovided by HGNC
Primary source
HGNC:HGNC:24600
See related
Ensembl:ENSG00000185046 MIM:607815; Vega:OTTHUMG00000170308
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EB1; AIDA; EB-1; ANKS2; AIDA-1; cajalin-2
Summary
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
Expression
Broad expression in brain (RPKM 8.0), thyroid (RPKM 1.1) and 21 other tissues See more
Orthologs

Genomic context

See ANKS1B in Genome Data Viewer
Location:
12q23.1
Exon count:
40
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 12 NC_000012.12 (98729904..99984773, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (99128569..100378512, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 3 Neighboring gene small nucleolar RNA, H/ACA box 53 Neighboring gene IKBKB interacting protein Neighboring gene apoptotic peptidase activating factor 1 Neighboring gene probable ribosome biogenesis protein RLP24 pseudogene Neighboring gene uncharacterized LOC101928937 Neighboring gene RNA, 5S ribosomal pseudogene 366 Neighboring gene family with sequence similarity 71 member C Neighboring gene UHRF1 binding protein 1 like Neighboring gene ribosomal protein S4X pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.
NHGRI GWA Catalog
Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.
NHGRI GWA Catalog
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
NHGRI GWA Catalog
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
NHGRI GWA Catalog
Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.
NHGRI GWA Catalog
Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.
NHGRI GWA Catalog
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
NHGRI GWA Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog

Pathways from BioSystems

  • Ectoderm Differentiation, organism-specific biosystem (from WikiPathways)
    Ectoderm Differentiation, organism-specific biosystemModel depicting ectoderm specification based on the literature and highly enriched gene expression profiles via comparison across dozens of independent induced and embryonic pluripotent stem cell lin...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC26087

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ephrin receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of synaptic plasticity by receptor localization to synapse IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Cajal body IEA
Inferred from Electronic Annotation
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
dendritic spine IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
 
postsynaptic density IEA
Inferred from Electronic Annotation
more info
 
postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ankyrin repeat and sterile alpha motif domain-containing protein 1B
Names
E2a-Pbx1-associated protein
amyloid-beta precursor protein intracellular domain associated protein 1
cajalin 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029860.1 RefSeqGene

    Range
    5001..1254864
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001204065.1NP_001190994.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform d

    See identical proteins and their annotated locations for NP_001190994.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (d) has a shorter N-terminus, a longer and distinct C-terminus, and an additional segment compared to isoform a.
    Source sequence(s)
    AC008126, AK315954, BC150204, BP193713, DB475766
    UniProtKB/Swiss-Prot
    Q7Z6G8
    UniProtKB/TrEMBL
    B7Z9I9
    Related
    OTTHUMP00000243464, OTTHUMT00000408430
    Conserved Domains (1) summary
    cd01274
    Location:76225
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  2. NM_001204066.1NP_001190995.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform e

    See identical proteins and their annotated locations for NP_001190995.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and coding region, in the 3' UTR and coding region, lacks an alternate in-frame segment, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (e) has a shorter N-terminus, a longer and distinct C-terminus, a missing segment, and an additional segment compared to isoform a.
    Source sequence(s)
    BC026313, BC068451, BC150204
    Consensus CDS
    CCDS55865.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000447312.2, OTTHUMP00000243461, ENST00000549025.6, OTTHUMT00000408427
    Conserved Domains (2) summary
    cd01274
    Location:144293
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:146
    SAM_superfamily; SAM (Sterile alpha motif )
  3. NM_001204067.1NP_001190996.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform f

    See identical proteins and their annotated locations for NP_001190996.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (f) has a shorter and distinct N-terminus, a longer and distinct C-terminus, and a missing segment compared to isoform a.
    Source sequence(s)
    AK294191, BC026313, BC068451, BC150204
    Consensus CDS
    CCDS55871.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000450015.1, OTTHUMP00000243463, ENST00000547446.5, OTTHUMT00000408429
    Conserved Domains (3) summary
    cd09499
    Location:672
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:77141
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:181330
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  4. NM_001204068.1NP_001190997.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform g

    See identical proteins and their annotated locations for NP_001190997.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and coding region and in the 3' UTR and coding region compared to variant 1. The resulting isoform (g, also known as AIDA-1a) has a shorter and distinct N-terminus and a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AY281132, BC026313, BC142669, BC150204, DA690060
    Consensus CDS
    CCDS55869.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000447839.1, OTTHUMP00000243468, ENST00000546960.5, OTTHUMT00000408435
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:272421
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  5. NM_001204069.1NP_001190998.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform h

    See identical proteins and their annotated locations for NP_001190998.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and coding region, in the 3' UTR and coding region, lacks an alternate in-frame exon, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (h) has a shorter and distinct N-terminus, a longer and distinct C-terminus, a missing segment, and an additional segment compared to isoform a.
    Source sequence(s)
    BC150204, DA690060
    Consensus CDS
    CCDS55868.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000447999.2, OTTHUMP00000243460, ENST00000550693.6, OTTHUMT00000408426
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:236385
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  6. NM_001204070.1NP_001190999.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform i

    See identical proteins and their annotated locations for NP_001190999.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (i, also known as AIDA-1c) has a shorter and distinct N-terminus, a longer and distinct C-terminus, and a missing segment compared to isoform a.
    Source sequence(s)
    AY753193, BC150204, DA690060
    Consensus CDS
    CCDS55867.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000448205.1, OTTHUMP00000243467, ENST00000546568.5, OTTHUMT00000408434
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:212361
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  7. NM_001204079.1NP_001191008.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform j

    See identical proteins and their annotated locations for NP_001191008.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (j) has a shorter N-terminus, a longer and distinct C-terminus, and an additional segment compared to isoform a.
    Source sequence(s)
    AC008126, AM980945, BC150204, BP193713, DB475766
    UniProtKB/Swiss-Prot
    Q7Z6G8
    UniProtKB/TrEMBL
    B1VKB5
    Conserved Domains (1) summary
    cd01274
    Location:77226
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  8. NM_001204080.1NP_001191009.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform k

    See identical proteins and their annotated locations for NP_001191009.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR and coding region and in the 3' UTR and coding region compared to variant 1. The resulting isoform (k) has a shorter and distinct N-terminus and a longer and distinct C-terminus compared to isoform a. Variants 11 and 39 both encode the same isoform (k).
    Source sequence(s)
    AC008126, AY356353, BC150204, BP193713, DB475766
    UniProtKB/Swiss-Prot
    Q7Z6G8
    UniProtKB/TrEMBL
    Q6V0K8
    Conserved Domains (1) summary
    cd01274
    Location:52201
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  9. NM_001204081.1NP_001191010.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform l

    See identical proteins and their annotated locations for NP_001191010.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (l) has a shorter and distinct N-terminus compared to isoform a.
    Source sequence(s)
    AC008126, AC011248, AK294994, BC142669, BP193713, DB475766
    Consensus CDS
    CCDS55864.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000345510.6, OTTHUMP00000272119, ENST00000341752.11, OTTHUMT00000408422
    Conserved Domains (1) summary
    cd01274
    Location:52201
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  10. NM_001352185.1NP_001339114.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform p

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
    Conserved Domains (5) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10461195
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  11. NM_001352186.1NP_001339115.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform m

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) represents the longest transcript and encodes the longest isoform (m).
    Source sequence(s)
    AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
    Conserved Domains (5) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10711220
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  12. NM_001352187.1NP_001339116.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform o

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
    Conserved Domains (5) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10461195
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  13. NM_001352188.1NP_001339117.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform n

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
    Conserved Domains (5) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10701219
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  14. NM_001352189.1NP_001339118.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform v

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:672
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:77141
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:265414
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  15. NM_001352190.1NP_001339119.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform qq

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:672
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:77141
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:266415
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  16. NM_001352191.1NP_001339120.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ee

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09500
    Location:51115
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:155304
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:146
    SAM_superfamily; SAM (Sterile alpha motif )
  17. NM_001352192.1NP_001339121.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform z

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09500
    Location:51115
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:215364
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:146
    SAM_superfamily; SAM (Sterile alpha motif )
  18. NM_001352193.1NP_001339122.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform y

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09500
    Location:51115
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:215364
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:146
    SAM_superfamily; SAM (Sterile alpha motif )
  19. NM_001352194.1NP_001339123.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform cc

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd01274
    Location:176325
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:108152
    SAM_superfamily; SAM (Sterile alpha motif )
  20. NM_001352195.1NP_001339124.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform r

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:296445
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  21. NM_001352196.1NP_001339125.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform s

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:296445
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  22. NM_001352197.1NP_001339126.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform w

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:272421
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  23. NM_001352198.1NP_001339127.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform q

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:297446
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  24. NM_001352199.1NP_001339128.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform aa

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:212361
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  25. NM_001352200.1NP_001339129.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform u

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:297446
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  26. NM_001352201.1NP_001339130.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform dd

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd01274
    Location:176325
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:108152
    SAM_superfamily; SAM (Sterile alpha motif )
  27. NM_001352202.1NP_001339131.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform pp

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:272421
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  28. NM_001352203.1NP_001339132.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform bb

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd01274
    Location:201350
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:108159
    SAM_superfamily; SAM (Sterile alpha motif )
  29. NM_001352204.1NP_001339133.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform t

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:272421
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  30. NM_001352205.1NP_001339134.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform oo

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:297446
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  31. NM_001352206.1NP_001339135.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform x

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248, AC079954, AC117377
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:236385
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  32. NM_001352207.1NP_001339136.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform k

    Status: REVIEWED

    Description
    Transcript Variant: This variant (39), as well as variant 11, encodes isoform k.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:52201
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  33. NM_001352208.1NP_001339137.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform gg

    Status: REVIEWED

    Description
    Transcript Variant: This variant (36), as well as variant 37, encodes isoform gg.
    Source sequence(s)
    AC008126, AC011248
    Consensus CDS
    CCDS86326.1
    Conserved Domains (1) summary
    cd01274
    Location:76225
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  34. NM_001352209.1NP_001339138.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ii

    Status: REVIEWED

    Description
    Transcript Variant: This variant (40), as well as variant 41, encodes isoform ii.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:52201
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  35. NM_001352210.1NP_001339139.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform kk

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:27176
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  36. NM_001352211.1NP_001339140.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

    Status: REVIEWED

    Description
    Transcript Variant: This variant (44), as well as variants 45, 46, 47, and 48, encodes isoform ll.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  37. NM_001352212.1NP_001339141.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

    Status: REVIEWED

    Description
    Transcript Variant: This variant (45), as well as variants 44, 46, 47, and 48, encodes isoform ll.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  38. NM_001352213.1NP_001339142.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform nn

    Status: REVIEWED

    Description
    Transcript Variant: This variant (50), as well as variants 51 and 52, encodes isoform nn.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  39. NM_001352214.1NP_001339143.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform nn

    Status: REVIEWED

    Description
    Transcript Variant: This variant (51), as well as variants 50 and 52, encodes isoform nn.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  40. NM_001352216.1NP_001339145.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform nn

    Status: REVIEWED

    Description
    Transcript Variant: This variant (52), as well as variants 50 and 51, encodes isoform nn.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  41. NM_001352217.1NP_001339146.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform mm

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  42. NM_001352218.1NP_001339147.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

    Status: REVIEWED

    Description
    Transcript Variant: This variant (46), as well as variants 44, 45, 47, and 48, encodes isoform ll.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  43. NM_001352219.1NP_001339148.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ff

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:77226
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  44. NM_001352220.1NP_001339149.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

    Status: REVIEWED

    Description
    Transcript Variant: This variant (47), as well as variants 44, 45, 46, and 48, encodes isoform ll.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  45. NM_001352221.1NP_001339150.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ii

    Status: REVIEWED

    Description
    Transcript Variant: This variant (41), as well as variant 40, encodes isoform ii.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:52201
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  46. NM_001352222.1NP_001339151.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform gg

    Status: REVIEWED

    Description
    Transcript Variant: This variant (37), as well as variant 36, encodes isoform gg.
    Source sequence(s)
    AC008126, AC011248
    Consensus CDS
    CCDS86326.1
    Related
    ENSP00000331256.7, ENST00000333732.11
    Conserved Domains (1) summary
    cd01274
    Location:76225
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  47. NM_001352223.1NP_001339152.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform hh

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:77226
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  48. NM_001352224.1NP_001339153.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

    Status: REVIEWED

    Description
    Transcript Variant: This variant (48), as well as variants 44, 45, 46, and 47, encodes isoform ll.
    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:1126
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  49. NM_001352225.1NP_001339154.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform jj

    Status: REVIEWED

    Source sequence(s)
    AC008126, AC011248
    Conserved Domains (1) summary
    cd01274
    Location:27176
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  50. NM_020140.3NP_064525.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform c

    See identical proteins and their annotated locations for NP_064525.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding region and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) has a shorter and distinct N-terminus and lacks an alternate segment compared to isoform a.
    Source sequence(s)
    AC011248, AC117377, BC142669, DA690060
    Consensus CDS
    CCDS55866.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000448993.2, OTTHUMP00000243458, ENST00000549558.6, OTTHUMT00000408423
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:212361
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  51. NM_152788.4NP_690001.3  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform a

    See identical proteins and their annotated locations for NP_690001.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform a (also known as AIDA-1b).
    Source sequence(s)
    AC011248, AK124453, AY281131, BC142669, DA183756, DA783474
    Consensus CDS
    CCDS55872.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000449629.2, OTTHUMP00000243457, ENST00000547776.6, OTTHUMT00000408421
    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10461195
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  52. NM_181670.3NP_858056.2  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform b

    See identical proteins and their annotated locations for NP_858056.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus, a longer and distinct C-terminus, and an additional segment compared to isoform a.
    Source sequence(s)
    BC026313, BC150204, DA690060
    Consensus CDS
    CCDS55870.1
    UniProtKB/Swiss-Prot
    Q7Z6G8
    Related
    ENSP00000448203.2, OTTHUMP00000243462, ENST00000549493.6, OTTHUMT00000408428
    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:296445
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p12 Primary Assembly

    Range
    98729904..99984773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006719507.4XP_006719570.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X4

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10711220
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  2. XM_006719514.4XP_006719577.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X17

    Conserved Domains (8) summary
    cd09499
    Location:807873
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:878942
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:804869
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:9821131
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  3. XM_017019654.2XP_016875143.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X6

  4. XM_017019658.2XP_016875147.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X16

  5. XM_017019653.2XP_016875142.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X5

  6. XM_024449070.1XP_024304838.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X27

    Conserved Domains (3) summary
    cd09500
    Location:51115
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:240389
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:146
    SAM_superfamily; SAM (Sterile alpha motif )
  7. XM_024449068.1XP_024304836.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X25

    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:263412
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  8. XM_005269029.5XP_005269086.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X9

    Conserved Domains (8) summary
    cd09499
    Location:807873
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:878942
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:804869
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10421191
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  9. XM_017019652.2XP_016875141.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X3

  10. XM_006719513.4XP_006719576.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X15

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:9861135
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  11. XM_006719512.4XP_006719575.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X14

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:9861135
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  12. XM_017019657.2XP_016875146.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

  13. XM_017019656.2XP_016875145.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X11

  14. XM_011538571.3XP_011536873.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X10

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10371186
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  15. XM_006719504.4XP_006719567.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X1

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10701219
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  16. XM_006719505.4XP_006719568.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X2

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10711220
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  17. XM_024449062.1XP_024304830.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X18

    Conserved Domains (3) summary
    cd09499
    Location:391457
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:462526
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:651800
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  18. XM_024449063.1XP_024304831.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X20

    Related
    ENSP00000448512.1, ENST00000547010.5
    Conserved Domains (3) summary
    cd09499
    Location:391457
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:462526
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:626775
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  19. XM_024449061.1XP_024304829.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X19

    Conserved Domains (3) summary
    cd09499
    Location:443509
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:514578
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:703852
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  20. XM_024449060.1XP_024304828.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X18

    Conserved Domains (3) summary
    cd09499
    Location:391457
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:462526
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:651800
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  21. XM_024449064.1XP_024304832.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X21

    Related
    ENSP00000448744.1, ENST00000550778.5
    Conserved Domains (3) summary
    cd09499
    Location:108174
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:179243
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:368517
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  22. XM_024449065.1XP_024304833.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X22

    Conserved Domains (3) summary
    cd09499
    Location:672
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:77141
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:266415
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  23. XM_024449069.1XP_024304837.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X26

    Conserved Domains (3) summary
    cd09500
    Location:51115
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:240389
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:146
    SAM_superfamily; SAM (Sterile alpha motif )
  24. XM_024449067.1XP_024304835.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X24

    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:262411
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  25. XM_024449066.1XP_024304834.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X23

    Conserved Domains (3) summary
    cd09499
    Location:37103
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:108172
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    cd01274
    Location:263412
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
  26. XM_006719508.4XP_006719571.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X7

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10711220
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  27. XM_006719510.4XP_006719573.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X12

    Conserved Domains (8) summary
    cd09499
    Location:811877
    SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
    cd09500
    Location:882946
    SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
    smart00454
    Location:808873
    SAM; Sterile alpha motif
    cd00204
    Location:53181
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01274
    Location:10461195
    PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
    pfam12796
    Location:63158
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:779
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:5889
    ANK; ANK repeat [structural motif]
  28. XM_017019655.2XP_016875144.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X8

RNA

  1. XR_001748815.2 RNA Sequence

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