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pofut4 protein O-fucosyltransferase 4 [ Danio rerio (zebrafish) ]

Gene ID: 568888, updated on 9-Sep-2025
Official Symbol
pofut4provided by ZNC
Official Full Name
protein O-fucosyltransferase 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-728
See related
Ensembl:ENSDARG00000102402 AllianceGenome:ZFIN:ZDB-GENE-060929-728
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fut11; zgc:153537
Summary
Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human FUT11 (fucosyltransferase 11). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See pofut4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 14 NC_133189.1 (16885623..16900615)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 14 NC_007125.7 (14608100..14622984)

Chromosome 14 - NC_133189.1Genomic Context describing neighboring genes Neighboring gene proteolipid protein 1a Neighboring gene RAB9B, member RAS oncogene family Neighboring gene zinc finger protein 185 with LIM domain Neighboring gene NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL Neighboring gene centrin, EF-hand protein, 2 Neighboring gene germ cell nuclear acidic peptidase

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC153537

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables alpha-(1->3)-fucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-(1->3)-fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide-O-fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide-O-fucosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in N-glycan fucosylation IEA
Inferred from Electronic Annotation
more info
  
involved_in fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of protein secretion ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
GDP-fucose protein O-fucosyltransferase 4
Names
alpha-(1,3)-fucosyltransferase 11
fuc-TXI
fucT-XI
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
fucosyltransferase XI
galactoside 3-L-fucosyltransferase 11
NP_001070642.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077174.1 → NP_001070642.1  GDP-fucose protein O-fucosyltransferase 4 precursor

    See identical proteins and their annotated locations for NP_001070642.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124380
    UniProtKB/Swiss-Prot
    Q08C60
    Related
    ENSDARP00000134474.1, ENSDART00000165099.2
    Conserved Domains (2) summary
    pfam00852
    Location:202 → 339
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:62 → 161
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133189.1 Reference GRCz12tu Primary Assembly

    Range
    16885623..16900615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08C60.1 GenPept UniProtKB/Swiss-Prot:Q08C60

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