Format

Send to:

Choose Destination

Dkk2 dickkopf WNT signaling pathway inhibitor 2 [ Mus musculus (house mouse) ]

Gene ID: 56811, updated on 12-Mar-2017
Official Symbol
Dkk2provided by MGI
Official Full Name
dickkopf WNT signaling pathway inhibitor 2provided by MGI
Primary source
MGI:MGI:1890663
See related
Ensembl:ENSMUSG00000028031 Vega:OTTMUSG00000054905
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
Location:
3; 3 G3
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (132085243..132180304)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (131748256..131843268)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene olfactory receptor 375, pseudogene 1 Neighboring gene predicted gene, 29865 Neighboring gene predicted gene, 29949 Neighboring gene predicted gene, 30147 Neighboring gene GIMAP family P-loop NTPase domain containing 1

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • BMP Signaling Pathway in Eyelid Development, organism-specific biosystem (from WikiPathways)
    BMP Signaling Pathway in Eyelid Development, organism-specific biosystemThe signaling pathways involved in eyelid development are displayed with interactions that are known (solid arrows) and proposed (dotted arrows). The four main pathways shown are activated by Fgf10 a...
  • Wnt signaling pathway, organism-specific biosystem (from KEGG)
    Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • Wnt signaling pathway, conserved biosystem (from KEGG)
    Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
co-receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of Wnt signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of canonical Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of canonical Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
dickkopf-related protein 2
Names
dickkopf 2
dickkopf homolog 1
dickkopf homolog 2
dkk-2
mDkk-2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020265.4NP_064661.2  dickkopf-related protein 2 precursor

    See identical proteins and their annotated locations for NP_064661.2

    Status: VALIDATED

    Source sequence(s)
    AC127260
    Consensus CDS
    CCDS17844.1
    UniProtKB/Swiss-Prot
    Q9QYZ8
    Related
    ENSMUSP00000029665, OTTMUSP00000071907, ENSMUST00000029665, OTTMUST00000136072
    Conserved Domains (1) summary
    pfam04706
    Location:78128
    Dickkopf_N; Dickkopf N-terminal cysteine-rich region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    132085243..132180304
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501818.3XP_006501881.1  dickkopf-related protein 2 isoform X1

    Conserved Domains (1) summary
    pfam04706
    Location:91141
    Dickkopf_N; Dickkopf N-terminal cysteine-rich region
Support Center