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pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta [ Danio rerio (zebrafish) ]

Gene ID: 567938, updated on 22-Nov-2020

Summary

Official Symbol
pik3c2bprovided by ZNC
Official Full Name
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 betaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050309-145
See related
Ensembl:ENSDARG00000086927
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:715046; im:7150469
Orthologs

Genomic context

See pik3c2b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
34
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (23595387..23696766, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (23354121..23458896, complement)
103 previous assembly Zv9 (GCF_000002035.4) 11 NC_007122.5 (24513152..24620039, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882447 Neighboring gene protein phosphatase 1 regulatory subunit 15B Neighboring gene neurofascin homolog (chicken) a Neighboring gene contactin 2

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
1-phosphatidylinositol-3-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
1-phosphatidylinositol-4-phosphate 3-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol 3-kinase signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol phosphorylation IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol-3-phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol-mediated signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol 3-kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Names
phosphoinositide-3-kinase, class 2, beta polypeptide
XP_003199535.1
XP_009304289.1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    23595387..23696766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003199487.5XP_003199535.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

    See identical proteins and their annotated locations for XP_003199535.1

    UniProtKB/TrEMBL
    F1QWN6
    Related
    ENSDARP00000110942.2, ENSDART00000124810.4
    Conserved Domains (6) summary
    cd00895
    Location:9341287
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd04012
    Location:569741
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:14581579
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cl00271
    Location:763928
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:322413
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl02563
    Location:13171425
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  2. XM_009306014.3XP_009304289.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

    See identical proteins and their annotated locations for XP_009304289.1

    UniProtKB/TrEMBL
    F1QWN6
    Related
    ENSDARP00000154070.1, ENSDART00000189599.1
    Conserved Domains (6) summary
    cd00895
    Location:9341287
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd04012
    Location:569741
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:14581579
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cl00271
    Location:763928
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:322413
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl02563
    Location:13171425
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
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