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Clec1b C-type lectin domain family 1, member b [ Mus musculus (house mouse) ]

Gene ID: 56760, updated on 1-May-2018

Summary

Official Symbol
Clec1bprovided by MGI
Official Full Name
C-type lectin domain family 1, member bprovided by MGI
Primary source
MGI:MGI:1913287
See related
Ensembl:ENSMUSG00000030159 Vega:OTTMUSG00000027001
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Clec2; Clec-2; 1810061I13Rik
Expression
Biased expression in liver E18 (RPKM 7.3), liver E14 (RPKM 6.1) and 8 other tissues See more
Orthologs

Genomic context

See Clec1b in Genome Data Viewer
Location:
6; 6 F3
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (129397297..129405413)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (129347315..129355351)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4922502D21 gene Neighboring gene C-type lectin domain family 12, member a Neighboring gene C-type lectin domain family 12, member B Neighboring gene C-type lectin domain family 9, member a Neighboring gene C-type lectin domain family 1, member a

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
transmembrane signaling receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
transmembrane signaling receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell surface receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
platelet formation IGI
Inferred from Genetic Interaction
more info
PubMed 
signal transduction by protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
C-type lectin domain family 1 member B
Names
C-type lectin-like receptor 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204239.1NP_001191168.1  C-type lectin domain family 1 member B isoform 2

    See identical proteins and their annotated locations for NP_001191168.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC138620
    Consensus CDS
    CCDS57452.1
    UniProtKB/Swiss-Prot
    Q9JL99
    Related
    ENSMUSP00000107712.2, OTTMUSP00000033487, ENSMUST00000112081.8, OTTMUST00000066731
    Conserved Domains (1) summary
    cd03593
    Location:70186
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
  2. NM_001204253.1NP_001191182.1  C-type lectin domain family 1 member B isoform 3

    See identical proteins and their annotated locations for NP_001191182.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two exons in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC138620
    Consensus CDS
    CCDS57453.1
    UniProtKB/TrEMBL
    A0T1G3
    Related
    ENSMUSP00000107710.2, OTTMUSP00000033488, ENSMUST00000112079.2, OTTMUST00000066732
  3. NM_019985.3NP_064369.1  C-type lectin domain family 1 member B isoform 1

    See identical proteins and their annotated locations for NP_064369.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC138620, BC064054
    Consensus CDS
    CCDS20586.1
    UniProtKB/Swiss-Prot
    Q9JL99
    Related
    ENSMUSP00000032262.7, OTTMUSP00000033486, ENSMUST00000032262.13, OTTMUST00000066730
    Conserved Domains (1) summary
    cd03593
    Location:102218
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    129397297..129405413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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