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zfr2 zinc finger RNA binding protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 567465, updated on 8-Mar-2025

Summary

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Official Symbol
zfr2provided by ZNC
Official Full Name
zinc finger RNA binding protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-070705-184
See related
Ensembl:ENSDARG00000071683 AllianceGenome:ZFIN:ZDB-GENE-070705-184
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zfr; wu:fb99a09; si:ch211-63j24.3
Summary
Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Orthologous to human ZFR2 (zinc finger RNA binding protein 2). [provided by Alliance of Genome Resources, Mar 2025]
Orthologs
all
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Genomic context

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See zfr2 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (5056288..5099841, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (4671914..4715514, complement)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene retinal homeobox gene 1 Neighboring gene megakaryocyte-associated tyrosine kinase Neighboring gene ATCAY kinesin light chain interacting caytaxin a Neighboring gene muscle-specific beta 1 integrin binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Common responses of fish embryos to metals: an integrated analysis of transcriptomes and methylomes in zebrafish embryos under the stress of copper ions or silver nanoparticles. Tai Z, et al. Metallomics, 2019 Sep 1. PMID 31468037
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC174987

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger RNA-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    5056288..5099841 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002666166.6 → XP_002666212.2  zinc finger RNA-binding protein isoform X2

    UniProtKB/TrEMBL
    A0A8M1RL31
    Conserved Domains (3) summary
    smart00572
    Location:717 → 967
    DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
    smart00451
    Location:524 → 555
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:315 → 337
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_005161603.5 → XP_005161660.1  zinc finger RNA-binding protein isoform X1

    UniProtKB/TrEMBL
    A0A8M2B8G8
    Related
    ENSDARP00000107390.3, ENSDART00000122341.5
    Conserved Domains (3) summary
    smart00572
    Location:718 → 968
    DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
    smart00451
    Location:524 → 555
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:315 → 337
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version

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