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Gpr132 G protein-coupled receptor 132 [ Mus musculus (house mouse) ]

Gene ID: 56696, updated on 9-Mar-2023

Summary

Official Symbol
Gpr132provided by MGI
Official Full Name
G protein-coupled receptor 132provided by MGI
Primary source
MGI:MGI:1890220
See related
Ensembl:ENSMUSG00000021298 AllianceGenome:MGI:1890220
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G2a
Summary
Predicted to enable G protein-coupled receptor activity. Involved in negative regulation of G2/M transition of mitotic cell cycle. Acts upstream of or within G1/S transition of mitotic cell cycle. Predicted to be integral component of plasma membrane. Is expressed in thymus primordium. Used to study autoimmune disease. Orthologous to human GPR132 (G protein-coupled receptor 132). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in thymus adult (RPKM 78.1), spleen adult (RPKM 34.3) and 2 other tissues See more
Orthologs
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Genomic context

See Gpr132 in Genome Data Viewer
Location:
12; 12 F1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (112814493..112832035, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (112850873..112868416, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene clathrin binding box of aftiphilin containing 1 Neighboring gene cell division cycle associated 4 Neighboring gene predicted gene, 52009 Neighboring gene predicted gene, 30461 Neighboring gene RIKEN cDNA 1700127F24 gene Neighboring gene jagged 2 Neighboring gene microRNA 6941

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
probable G-protein coupled receptor 132
Names
G protein-coupled receptor G2A
G2 accumulation protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019925.4NP_064309.1  probable G-protein coupled receptor 132

    See identical proteins and their annotated locations for NP_064309.1

    Status: PROVISIONAL

    Source sequence(s)
    AK153765
    Consensus CDS
    CCDS26199.1
    UniProtKB/Swiss-Prot
    Q3U5A4, Q9Z282
    Related
    ENSMUSP00000021729.8, ENSMUST00000021729.9
    Conserved Domains (2) summary
    cd14964
    Location:4666
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:46317
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    112814493..112832035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516102.4XP_006516165.1  probable G-protein coupled receptor 132 isoform X1

    See identical proteins and their annotated locations for XP_006516165.1

    UniProtKB/Swiss-Prot
    Q3U5A4, Q9Z282
    Conserved Domains (2) summary
    cd14964
    Location:4666
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:46317
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. XM_006516103.2XP_006516166.1  probable G-protein coupled receptor 132 isoform X1

    See identical proteins and their annotated locations for XP_006516166.1

    UniProtKB/Swiss-Prot
    Q3U5A4, Q9Z282
    Conserved Domains (2) summary
    cd14964
    Location:4666
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:46317
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily