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Crtap cartilage associated protein [ Mus musculus (house mouse) ]

Gene ID: 56693, updated on 26-Sep-2022


Official Symbol
Crtapprovided by MGI
Official Full Name
cartilage associated proteinprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000032431 AllianceGenome:MGI:1891221
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CASP; P3h5; Leprel3; 5730529N23Rik
Predicted to contribute to collagen binding activity. Acts upstream of or within peptidyl-proline hydroxylation to 3-hydroxy-L-proline and spermatogenesis. Located in endoplasmic reticulum. Is expressed in several structures, including dermis; genitourinary system; heart; rib; and stomach. Used to study osteogenesis imperfecta type 7. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 7. Orthologous to human CRTAP (cartilage associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Broad expression in adrenal adult (RPKM 194.8), ovary adult (RPKM 168.2) and 16 other tissues See more
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Genomic context

See Crtap in Genome Data Viewer
9; 9 F3
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (114204199..114219780, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (114375131..114390712, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930525D18 gene Neighboring gene B cell leukemia/lymphoma 2 related protein A1c Neighboring gene RIKEN cDNA 4930520O04 gene Neighboring gene transmembrane protein with metallophosphoesterase domain Neighboring gene galactosidase, beta 1 Neighboring gene predicted gene, 30254

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1)  1 citation
  • Endonuclease-mediated (3) 

Pathways from PubChem

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to collagen binding IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
located_in extracellular space ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
cartilage-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019922.3NP_064306.2  cartilage-associated protein precursor

    See identical proteins and their annotated locations for NP_064306.2

    Status: VALIDATED

    Source sequence(s)
    Consensus CDS
    Q8C8C5, Q9CYD3
    ENSMUSP00000081941.5, ENSMUST00000084881.5

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000075.7 Reference GRCm39 C57BL/6J

    114204199..114219780 complement
    GenBank, FASTA, Sequence Viewer (Graphics)