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Dnajb8 DnaJ heat shock protein family (Hsp40) member B8 [ Mus musculus (house mouse) ]

Gene ID: 56691, updated on 1-Mar-2024

Summary

Official Symbol
Dnajb8provided by MGI
Official Full Name
DnaJ heat shock protein family (Hsp40) member B8provided by MGI
Primary source
MGI:MGI:1922801
See related
Ensembl:ENSMUSG00000048206 AllianceGenome:MGI:1922801
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mDj6; 1700016F14Rik; 1700031F10Rik
Summary
Predicted to enable chaperone binding activity; protein folding chaperone; and unfolded protein binding activity. Predicted to be involved in chaperone-mediated protein folding and negative regulation of inclusion body assembly. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in brain. Orthologous to human DNAJB8 (DnaJ heat shock protein family (Hsp40) member B8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Dnajb8 in Genome Data Viewer
Location:
6 D1; 6 39.25 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (88199250..88200238)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (88222268..88223256)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene stem and progenitor enriched required for hematopoietic differentiation Neighboring gene predicted gene, 38856 Neighboring gene Gata2R7 and Gata2R8 erythroid cis-regulatory modules Neighboring gene GATA binding protein 2 Neighboring gene Gata2R5 erythroid cis-regulatory module Neighboring gene Gata2R6 erythroid cis-regulatory module Neighboring gene predicted gene, 57776 Neighboring gene eukaryotic elongation factor, selenocysteine-tRNA-specific Neighboring gene predicted gene, 44264

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables Hsp70 protein binding IEA
Inferred from Electronic Annotation
more info
 
enables protein folding chaperone IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein folding chaperone ISO
Inferred from Sequence Orthology
more info
 
enables protein-folding chaperone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein-folding chaperone binding ISO
Inferred from Sequence Orthology
more info
 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables unfolded protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in chaperone-mediated protein folding IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within chaperone-mediated protein folding ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of inclusion body assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dnaJ homolog subfamily B member 8
Names
DnaJ (Hsp40) homolog, subfamily B, member 8
DnaJ homolog 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019964.1NP_064348.1  dnaJ homolog subfamily B member 8

    See identical proteins and their annotated locations for NP_064348.1

    Status: PROVISIONAL

    Source sequence(s)
    AB028856
    Consensus CDS
    CCDS20334.1
    UniProtKB/Swiss-Prot
    Q9QYI7
    Related
    ENSMUSP00000056592.5, ENSMUST00000061866.6
    Conserved Domains (1) summary
    pfam00226
    Location:366
    DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    88199250..88200238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)