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EIF5A2 eukaryotic translation initiation factor 5A2 [ Homo sapiens (human) ]

Gene ID: 56648, updated on 9-Dec-2018

Summary

Official Symbol
EIF5A2provided by HGNC
Official Full Name
eukaryotic translation initiation factor 5A2provided by HGNC
Primary source
HGNC:HGNC:3301
See related
Ensembl:ENSG00000163577 MIM:605782
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EIF-5A2; eIF5AII
Expression
Ubiquitous expression in brain (RPKM 2.4), testis (RPKM 2.3) and 25 other tissues See more
Orthologs

Genomic context

See EIF5A2 in Genome Data Viewer
Location:
3q26.2
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (170888415..170908637, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (170606204..170626426, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene RNY5 pseudogene 3 Neighboring gene ribosomal protein L22 like 1 Neighboring gene kruppel like factor 7 pseudogene 1 Neighboring gene RNA, U1 small nuclear 70, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ribosome binding IEA
Inferred from Electronic Annotation
more info
 
translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
mRNA transport IEA
Inferred from Electronic Annotation
more info
 
polyamine homeostasis NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of translational elongation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of translational termination IEA
Inferred from Electronic Annotation
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis NAS
Non-traceable Author Statement
more info
PubMed 
translational frameshifting IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
nuclear pore IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 5A-2
Names
eIF-5A-2
eukaryotic initiation factor 5A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020390.6NP_065123.1  eukaryotic translation initiation factor 5A-2

    See identical proteins and their annotated locations for NP_065123.1

    Status: VALIDATED

    Source sequence(s)
    AY205261
    Consensus CDS
    CCDS3214.1
    UniProtKB/Swiss-Prot
    Q9GZV4
    Related
    ENSP00000295822.2, ENST00000295822.6
    Conserved Domains (1) summary
    cl28432
    Location:1150
    PRK03999; translation initiation factor IF-5A; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    170888415..170908637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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