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vmn2r1 vomeronasal 2, receptor 1 [ Danio rerio (zebrafish) ]

Gene ID: 566039, updated on 11-Apr-2024

Summary

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Official Symbol
vmn2r1provided by ZNC
Official Full Name
vomeronasal 2, receptor 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-050419-65
See related
Ensembl:ENSDARG00000005942 AllianceGenome:ZFIN:ZDB-GENE-050419-65
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
VR5.3; v2rl1; v2r2l1; si:ch211-141o12.1
Summary
Enables olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in heart; microvillous olfactory receptor neurons; olfactory epithelium; and olfactory rosette. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
chromosome: 18
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (34225369..34243080)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (34249345..34267056)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene c18h3orf33 homolog (H. sapiens) Neighboring gene solute carrier family 33 member 1 Neighboring gene guanine monophosphate synthase Neighboring gene uncharacterized LOC103909166 Neighboring gene potassium voltage-gated channel subfamily A regulatory beta subunit 1a Neighboring gene signal sequence receptor, gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Role of a ubiquitously expressed receptor in the vertebrate olfactory system. DeMaria S, et al. J Neurosci, 2013 Sep 18. PMID 24048853, Free PMC Article
  2. Mutually exclusive glomerular innervation by two distinct types of olfactory sensory neurons revealed in transgenic zebrafish. Sato Y, et al. J Neurosci, 2005 May 18. PMID 15901770, Free PMC Article
  3. Patterned Arrangements of Olfactory Receptor Gene Expression in Zebrafish are Established by Radial Movement of Specified Olfactory Sensory Neurons. Bayramli X, et al. Sci Rep, 2017 Jul 17. PMID 28717156, Free PMC Article
  4. Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening. Ding Y, et al. Circ Res, 2013 Feb 15. PMID 23283723, Free PMC Article
  5. Crypt neurons express a single V1R-related ora gene. Oka Y, et al. Chem Senses, 2012 Mar. PMID 22038944

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables signaling receptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
vomeronasal type-2 receptor 1
Names
L01
OlfCc1
V2R2
odorant receptor VR5.3
v2r9
vomeronasal 2 receptor, l1
vomeronasal 2, receptor, 2-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    34225369..34243080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009293770.2 → XP_009292045.1  vomeronasal type-2 receptor 1

    UniProtKB/TrEMBL
    A0A8M3AV12, A8E7K1
    Related
    ENSDARP00000106663.2, ENSDART00000126115.3
    Conserved Domains (4) summary
    pfam00003
    Location:612 → 876
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:88 → 484
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:527 → 578
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:47 → 509
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version

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