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meltf melanotransferrin [ Danio rerio (zebrafish) ]

Gene ID: 565942, updated on 9-Dec-2024

Summary

Official Symbol
meltfprovided by ZNC
Official Full Name
melanotransferrinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050309-40
See related
Ensembl:ENSDARG00000075159 AllianceGenome:ZFIN:ZDB-GENE-050309-40
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mfi2; im:7143617
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in iron ion transport. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in extracellular region. Predicted to be active in endosome; extracellular space; and plasma membrane. Is expressed in gut; intestinal bulb; otic vesicle; and pectoral fin. Orthologous to human MELTF (melanotransferrin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See meltf in Genome Data Viewer
Location:
chromosome: 6
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (30091811..30109428)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (30101207..30120179)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438688 Neighboring gene discs large MAGUK scaffold protein 1a Neighboring gene uncharacterized LOC137495973 Neighboring gene leucine rich repeat containing 40 Neighboring gene leucine rich repeat containing 7

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within iron ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
melanotransferrin
Names
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    30091811..30109428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009302441.4XP_009300716.1  melanotransferrin isoform X1

    UniProtKB/TrEMBL
    A0A8M3B3G9
    Conserved Domains (3) summary
    smart00094
    Location:360689
    TR_FER; Transferrin
    cd13529
    Location:22343
    PBP2_transferrin; Transferrin family of the type 2 periplasmic-binding protein superfamily
    cl21456
    Location:358689
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
  2. XM_689207.10XP_694299.4  melanotransferrin isoform X2

    UniProtKB/TrEMBL
    A0A8N7TE96, E7F2E3
    Related
    ENSDARP00000082836.5, ENSDART00000088403.7
    Conserved Domains (3) summary
    smart00094
    Location:359688
    TR_FER; Transferrin
    cd13529
    Location:22342
    PBP2_transferrin; Transferrin family of the type 2 periplasmic-binding protein superfamily
    cl21456
    Location:357688
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily