U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

phkg1a phosphorylase kinase, gamma 1a (muscle) [ Danio rerio (zebrafish) ]

Gene ID: 565379, updated on 14-May-2025
Official Symbol
phkg1aprovided by ZNC
Official Full Name
phosphorylase kinase, gamma 1a (muscle)provided by ZNC
Primary source
ZFIN:ZDB-GENE-061103-385
See related
Ensembl:ENSDARG00000030604 AllianceGenome:ZFIN:ZDB-GENE-061103-385
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153009
Summary
Predicted to enable phosphorylase kinase activity. Acts upstream of or within angiogenesis. Predicted to be part of phosphorylase kinase complex. Predicted to be active in cytoplasm. Orthologous to human PHKG1 (phosphorylase kinase catalytic subunit gamma 1). [provided by Alliance of Genome Resources, May 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table
See phkg1a in Genome Data Viewer
Location:
chromosome: 15
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 15 NC_133190.1 (5985571..6005672, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 15 NC_007126.7 (5722530..5742531, complement)

Chromosome 15 - NC_133190.1Genomic Context describing neighboring genes Neighboring gene bromodomain and WD repeat domain containing 1 Neighboring gene uncharacterized LOC141378006 Neighboring gene melanocortin 2 receptor accessory protein Neighboring gene URB1 ribosome biogenesis homolog Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 2

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish. Camus S, et al. Oncogene, 2012 Sep 27. PMID 22179836
  2. Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome. Kumar MG, et al. eNeuro, 2016 Mar-Apr. PMID 27066534, Free PMC Article
  3. Ribosome biogenesis protein Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish. He J, et al. J Genet Genomics, 2017 Dec 20. PMID 29246861
  4. Transcriptional and metabolic effects of glucocorticoid receptor α and β signaling in zebrafish. Chatzopoulou A, et al. Endocrinology, 2015 May. PMID 25756310
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC153009

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphorylase kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphorylase kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within angiogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycogen metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of phosphorylase kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of phosphorylase kinase complex IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
phosphorylase kinase, gamma 1a (muscle)
NP_001071080.1
XP_073779251.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077612.1 → NP_001071080.1  phosphorylase kinase, gamma 1a (muscle)

    See identical proteins and their annotated locations for NP_001071080.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125847
    UniProtKB/TrEMBL
    A0JME5, B2GPU8, F6NQ90
    Related
    ENSDARP00000045984.5, ENSDART00000045985.7
    Conserved Domains (2) summary
    smart00220
    Location:20 → 288
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14182
    Location:16 → 291
    STKc_PhKG1; Catalytic domain of the Serine/Threonine Kinase, Phosphorylase kinase Gamma 1 subunit

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133190.1 Reference GRCz12tu Primary Assembly

    Range
    5985571..6005672 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_073923150.1 → XP_073779251.1  phosphorylase kinase, gamma 1a (muscle) isoform X1

RNA

  1. XR_012390542.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools