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Cnpy2 canopy FGF signaling regulator 2 [ Mus musculus (house mouse) ]

Gene ID: 56530, updated on 6-Jun-2024

Summary

Official Symbol
Cnpy2provided by MGI
Official Full Name
canopy FGF signaling regulator 2provided by MGI
Primary source
MGI:MGI:1928477
See related
Ensembl:ENSMUSG00000025381 AllianceGenome:MGI:1928477
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tmem4; Zsig9; D10Bwg1546e; 5330432A10Rik
Summary
Predicted to be active in endoplasmic reticulum. Is expressed in embryo. Orthologous to human CNPY2 (canopy FGF signaling regulator 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 39.1), limb E14.5 (RPKM 36.9) and 28 other tissues See more
Orthologs
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Genomic context

See Cnpy2 in Genome Data Viewer
Location:
10 D3; 10 76.52 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (128157972..128163056)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (128322158..128327187)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E194 Neighboring gene interleukin 23, alpha subunit p19 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:127740631-127740818 Neighboring gene predicted gene, 23241 Neighboring gene PAN2 poly(A) specific ribonuclease subunit Neighboring gene STARR-positive B cell enhancer ABC_E9813 Neighboring gene STARR-positive B cell enhancer ABC_E1134 Neighboring gene STARR-positive B cell enhancer ABC_E11467 Neighboring gene citrate synthase Neighboring gene predicted gene, 23182 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:127806017-127806126 Neighboring gene coenzyme Q10A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 
  • Targeted (2)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein canopy homolog 2
Names
MIR-interacting saposin-like protein
canopy 2 homolog
putative secreted protein ZSIG9
transmembrane protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429229.1NP_001416158.1  protein canopy homolog 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC090489
    UniProtKB/Swiss-Prot
    Q3UBH8, Q9QXT0
  2. NM_001429230.1NP_001416159.1  protein canopy homolog 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC090489
    UniProtKB/Swiss-Prot
    Q3UBH8, Q9QXT0
  3. NM_001429231.1NP_001416160.1  protein canopy homolog 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC090489
    UniProtKB/Swiss-Prot
    Q3UBH8, Q9QXT0
  4. NM_001429232.1NP_001416161.1  protein canopy homolog 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC090489
    UniProtKB/Swiss-Prot
    Q3UBH8, Q9QXT0
  5. NM_019953.2NP_064337.1  protein canopy homolog 2 precursor

    See identical proteins and their annotated locations for NP_064337.1

    Status: VALIDATED

    Source sequence(s)
    AC090489
    Consensus CDS
    CCDS24272.1
    UniProtKB/Swiss-Prot
    Q3UBH8, Q9QXT0
    Related
    ENSMUSP00000151918.2, ENSMUST00000219037.2
    Conserved Domains (1) summary
    pfam11938
    Location:27165
    DUF3456; TLR4 regulator and MIR-interacting MSAP

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    128157972..128163056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513902.5XP_006513965.1  protein canopy homolog 2 isoform X2

    Related
    ENSMUSP00000026446.3, ENSMUST00000026446.4
    Conserved Domains (1) summary
    pfam11938
    Location:27165
    DUF3456; TLR4 regulator and MIR-interacting MSAP
  2. XM_030245184.2XP_030101044.1  protein canopy homolog 2 isoform X1

    Conserved Domains (1) summary
    pfam11938
    Location:46184
    DUF3456; TLR4 regulator and MIR-interacting MSAP