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cenpk centromere protein K [ Danio rerio (zebrafish) ]

Gene ID: 565144, updated on 9-Sep-2025
Official Symbol
cenpkprovided by ZNC
Official Full Name
centromere protein Kprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090313-204
See related
Ensembl:ENSDARG00000039616 AllianceGenome:ZFIN:ZDB-GENE-090313-204
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-179o14.3
Summary
Predicted to be involved in mitotic sister chromatid segregation. Predicted to act upstream of or within kinetochore assembly. Predicted to be located in chromosome, centromeric region and nucleus. Orthologous to human CENPK (centromere protein K). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See cenpk in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 1 NC_133176.1 (35086887..35094255, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 1 NC_007112.7 (31508735..31516148, complement)

Chromosome 1 - NC_133176.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC141385803 Neighboring gene potassium voltage-gated channel, KQT-like subfamily, member 5b Neighboring gene regulating synaptic membrane exocytosis 1b Neighboring gene uncharacterized LOC141385860 Neighboring gene ladybird homeobox 1b Neighboring gene solute carrier family 2 member 15b

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. The splicing factor Prpf31 is required for hematopoietic stem and progenitor cell expansion during zebrafish embryogenesis. Lv Y, et al. J Biol Chem, 2024 Mar. PMID 38382674, Free PMC Article
  2. Dhx38 is required for the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing. Tu J, et al. Development, 2022 Sep 1. PMID 35929537
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within kinetochore assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic sister chromatid segregation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
centromere protein K
Names
SoxLZ/Sox6 leucine zipper binding protein

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256665.3 → NP_001243594.3  centromere protein K

    Status: VALIDATED

    Source sequence(s)
    JBMGRA010000001
    Related
    ENSDARP00000123524.1, ENSDART00000146567.3

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133176.1 Reference GRCz12tu Primary Assembly

    Range
    35086887..35094255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068220401.2 → XP_068076502.2  centromere protein K isoform X1

    UniProtKB/TrEMBL
    A0AB32TP46

  2. XM_073947836.1 → XP_073803937.1  centromere protein K isoform X3

  3. XM_073947832.1 → XP_073803933.1  centromere protein K isoform X2

RNA

  1. XR_012402240.1 RNA Sequence

  2. XR_012402241.1 RNA Sequence

  3. XR_012402239.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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