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RPRM reprimo, TP53 dependent G2 arrest mediator homolog [ Homo sapiens (human) ]

Gene ID: 56475, updated on 22-Sep-2022

Summary

Official Symbol
RPRMprovided by HGNC
Official Full Name
reprimo, TP53 dependent G2 arrest mediator homologprovided by HGNC
Primary source
HGNC:HGNC:24201
See related
Ensembl:ENSG00000177519 MIM:612171; AllianceGenome:HGNC:24201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
REPRIMO
Summary
Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See RPRM in Genome Data Viewer
Location:
2q23.3
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (153477338..153478762, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (153929892..153931316, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (154333852..154335276, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD56 Neighboring gene tubulin alpha pseudogene 13 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 13 Neighboring gene DnaJ heat shock protein family (Hsp40) member A1 pseudogene 2 Neighboring gene PHB1 pseudogene 4

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90327

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of cell cycle TAS
Traceable Author Statement
more info
PubMed 
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein reprimo
Names
candidate mediator of the p53 dependent G2 arrest
reprimo, TP53 dependant G2 arrest mediator candidate
reprimo, TP53 dependent G2 arrest mediator candidate

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019845.3NP_062819.1  protein reprimo

    See identical proteins and their annotated locations for NP_062819.1

    Status: VALIDATED

    Source sequence(s)
    AA452090, BC002908
    Consensus CDS
    CCDS2198.1
    UniProtKB/Swiss-Prot
    B2R4V1, Q9NS64
    Related
    ENSP00000314946.3, ENST00000325926.4

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    153477338..153478762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    153929892..153931316 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)