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Stmn4 stathmin-like 4 [ Mus musculus (house mouse) ]

Gene ID: 56471, updated on 9-Sep-2018

Summary

Official Symbol
Stmn4provided by MGI
Official Full Name
stathmin-like 4provided by MGI
Primary source
MGI:MGI:1931224
See related
Ensembl:ENSMUSG00000022044 Vega:OTTMUSG00000027814
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RB3; Lagl; R75359
Expression
Biased expression in CNS E18 (RPKM 183.1), CNS E14 (RPKM 102.9) and 5 other tissues See more
Orthologs

Genomic context

See Stmn4 in Genome Data Viewer
Location:
14; 14 D1
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (66344296..66361680)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66963212..66980517)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700001G11 gene Neighboring gene tripartite motif-containing 35 Neighboring gene predicted gene, 41183 Neighboring gene predicted gene, 41184 Neighboring gene adrenergic receptor, alpha 1a

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
microtubule depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of microtubule polymerization or depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
stathmin-4
Names
stathmin-like protein B3
stathmin-like protein RB3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310522.1NP_001297451.1  stathmin-4 isoform 1

    See identical proteins and their annotated locations for NP_001297451.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    BC046752, BQ178328, CD776693, CJ062344, CO427355
    Consensus CDS
    CCDS79339.1
    UniProtKB/Swiss-Prot
    P63042
    UniProtKB/TrEMBL
    G3X9Z6
    Related
    ENSMUSP00000113759.1, OTTMUSP00000034882, ENSMUST00000120229.7, OTTMUST00000068839
    Conserved Domains (1) summary
    pfam00836
    Location:76211
    Stathmin; Stathmin family
  2. NM_001310523.1NP_001297452.1  stathmin-4 isoform 3

    See identical proteins and their annotated locations for NP_001297452.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR. It encodes isoform 3 which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BC046752, BE859440, CD776693, CJ062344
    Consensus CDS
    CCDS79340.1
    UniProtKB/Swiss-Prot
    P63042
    UniProtKB/TrEMBL
    Q05DI3
    Related
    ENSMUSP00000113629.1, OTTMUSP00000034881, ENSMUST00000118426.7, OTTMUST00000068838
    Conserved Domains (1) summary
    pfam00836
    Location:49171
    Stathmin; Stathmin family
  3. NM_019675.3NP_062649.1  stathmin-4 isoform 2

    See identical proteins and their annotated locations for NP_062649.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.
    Source sequence(s)
    BC046752, CJ062344
    Consensus CDS
    CCDS27222.1
    UniProtKB/Swiss-Prot
    P63042
    Related
    ENSMUSP00000074113.6, OTTMUSP00000034880, ENSMUST00000074523.12, OTTMUST00000068837
    Conserved Domains (1) summary
    pfam00836
    Location:49184
    Stathmin; Stathmin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    66344296..66361680
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519316.2XP_006519379.1  stathmin-4 isoform X1

    See identical proteins and their annotated locations for XP_006519379.1

    UniProtKB/TrEMBL
    D3Z4C2
    Related
    ENSMUSP00000113788.1, OTTMUSP00000034883, ENSMUST00000121955.7, OTTMUST00000068840
    Conserved Domains (1) summary
    pfam00836
    Location:80198
    Stathmin; Stathmin family
  2. XM_017316097.1XP_017171586.1  stathmin-4 isoform X2

    UniProtKB/TrEMBL
    Q05DI3
    Conserved Domains (1) summary
    pfam00836
    Location:49171
    Stathmin; Stathmin family
  3. XM_006519317.2XP_006519380.1  stathmin-4 isoform X1

    See identical proteins and their annotated locations for XP_006519380.1

    UniProtKB/TrEMBL
    D3Z4C2
    Conserved Domains (1) summary
    pfam00836
    Location:80198
    Stathmin; Stathmin family
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