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usp31 ubiquitin specific peptidase 31 [ Danio rerio (zebrafish) ]

Gene ID: 564487, updated on 11-Apr-2024

Summary

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Official Symbol
usp31provided by ZNC
Official Full Name
ubiquitin specific peptidase 31provided by ZNC
Primary source
ZFIN:ZDB-GENE-100210-4
See related
Ensembl:ENSDARG00000074017 AllianceGenome:ZFIN:ZDB-GENE-100210-4
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable thiol-dependent deubiquitinase. Predicted to act upstream of or within protein deubiquitination and ubiquitin-dependent protein catabolic process. Orthologous to human USP31 (ubiquitin specific peptidase 31). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (45192510..45246910, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (47240176..47294602, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene heparan sulfate (glucosamine) 3-O-sulfotransferase 4 Neighboring gene heparan sulfate (glucosamine) 3-O-sulfotransferase 2 Neighboring gene potassium channel tetramerization domain containing 5a Neighboring gene 3-phosphoinositide dependent protein kinase 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development. Tse WK, et al. BMC Genomics, 2009 Dec 30. PMID 20040115, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 31
XP_005164285.1
XP_005164286.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    45192510..45246910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005164228.4 → XP_005164285.1  ubiquitin carboxyl-terminal hydrolase 31 isoform X1

    UniProtKB/TrEMBL
    A0A2R8QST4, A0A8M2BBF5
    Related
    ENSDARP00000156523.1, ENSDART00000181003.1
    Conserved Domains (3) summary
    COG5560
    Location:82 → 732
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:562 → 729
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl02553
    Location:92 → 302
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  2. XM_005164229.4 → XP_005164286.1  ubiquitin carboxyl-terminal hydrolase 31 isoform X2

    UniProtKB/TrEMBL
    A0A2R8Q2V8, A0A8M2BBS6
    Related
    ENSDARP00000146973.1, ENSDART00000193586.1
    Conserved Domains (3) summary
    COG5560
    Location:82 → 732
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:562 → 729
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl02553
    Location:92 → 302
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
Nucleotide Protein Strain
Heading Accession and Version

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