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pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 [ Danio rerio (zebrafish) ]

Gene ID: 564088, updated on 17-Nov-2020

Summary

Official Symbol
pik3r4provided by ZNC
Official Full Name
phosphoinositide-3-kinase, regulatory subunit 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-050309-84
See related
Ensembl:ENSDARG00000060469
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
vp; vps15; im:714878; im:7148788
Orthologs

Genomic context

See pik3r4 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
21
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (36721230..36748460, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (36767346..36794581, complement)
103 previous assembly Zv9 (GCF_000002035.4) 16 NC_007127.5 (38126863..38154103, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase pim-3-like Neighboring gene uncharacterized LOC103908963 Neighboring gene collagen, type VI, alpha 4a Neighboring gene 2,4-dienoyl CoA reductase 1, mitochondrial Neighboring gene calbindin 1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
autophagy of peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
late endosome to vacuole transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein targeting to vacuole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
endosome IEA
Inferred from Electronic Annotation
more info
 
late endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus-vacuole junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol 3-kinase complex, class III, type I IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol 3-kinase complex, class III, type II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
phosphoinositide 3-kinase regulatory subunit 4
XP_001922676.1
XP_005158356.1
XP_021322650.1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    36721230..36748460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158299.4XP_005158356.1  phosphoinositide 3-kinase regulatory subunit 4 isoform X3

    UniProtKB/TrEMBL
    E9QFS6
    Related
    ENSDARP00000115670.1, ENSDART00000133310.3
    Conserved Domains (7) summary
    smart00320
    Location:13091340
    WD40; WD40 repeats
    smart00220
    Location:26304
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG2319
    Location:9691340
    WD40; WD40 repeat [General function prediction only]
    cd13980
    Location:25315
    STKc_Vps15; Catalytic domain of the Serine/Threonine kinase, Vacuolar protein sorting-associated protein 15
    sd00044
    Location:543570
    HEAT; HEAT repeat [structural motif]
    sd00039
    Location:10241069
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:9611247
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_001922641.6XP_001922676.1  phosphoinositide 3-kinase regulatory subunit 4 isoform X1

    Conserved Domains (7) summary
    smart00320
    Location:13531384
    WD40; WD40 repeats
    smart00220
    Location:26304
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG2319
    Location:10131384
    WD40; WD40 repeat [General function prediction only]
    cd13980
    Location:25315
    STKc_Vps15; Catalytic domain of the Serine/Threonine kinase, Vacuolar protein sorting-associated protein 15
    sd00044
    Location:543570
    HEAT; HEAT repeat [structural motif]
    sd00039
    Location:10681113
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:10051291
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_021466975.1XP_021322650.1  phosphoinositide 3-kinase regulatory subunit 4 isoform X2

    Related
    ENSDARP00000079663.5, ENSDART00000085228.6
    Conserved Domains (5) summary
    smart00320
    Location:13161347
    WD40; WD40 repeats
    cd13980
    Location:25315
    STKc_Vps15; Catalytic domain of the Serine/Threonine kinase, Vacuolar protein sorting-associated protein 15
    sd00044
    Location:543570
    HEAT; HEAT repeat [structural motif]
    sd00039
    Location:10311076
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:9681254
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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