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Copz2 coatomer protein complex, subunit zeta 2 [ Mus musculus (house mouse) ]

Gene ID: 56358, updated on 11-Apr-2024

Summary

Official Symbol
Copz2provided by MGI
Official Full Name
coatomer protein complex, subunit zeta 2provided by MGI
Primary source
MGI:MGI:1929008
See related
Ensembl:ENSMUSG00000018672 AllianceGenome:MGI:1929008
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
zeta2-COP; 1110012D12Rik
Summary
Predicted to be involved in intra-Golgi vesicle-mediated transport; intracellular protein transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be located in COPI-coated vesicle. Predicted to be part of COPI vesicle coat. Orthologous to human COPZ2 (COPI coat complex subunit zeta 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 34.8), limb E14.5 (RPKM 33.8) and 28 other tissues See more
Orthologs
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Genomic context

Location:
11 D; 11 60.13 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (96740702..96752029)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (96849876..96861203)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene chromobox 1 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_30564 Neighboring gene STARR-seq mESC enhancer starr_30565 Neighboring gene STARR-positive B cell enhancer ABC_E9144 Neighboring gene nuclear factor, erythroid derived 2,-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E9371 Neighboring gene STARR-positive B cell enhancer ABC_E201 Neighboring gene microRNA 152 Neighboring gene STARR-positive B cell enhancer ABC_E2366 Neighboring gene predicted gene 11523 Neighboring gene VISTA enhancer mm1299 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene VISTA enhancers mm876 and mm999 Neighboring gene STARR-seq mESC enhancer starr_30571 Neighboring gene predicted gene, 38961 Neighboring gene VISTA enhancer mm1675

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of COPI vesicle coat ISO
Inferred from Sequence Orthology
more info
 
located_in COPI-coated vesicle ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coatomer subunit zeta-2
Names
nonclathrin coat protein zeta2-COP
zeta-2 COP
zeta-2-coat protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019877.2NP_063930.1  coatomer subunit zeta-2

    See identical proteins and their annotated locations for NP_063930.1

    Status: VALIDATED

    Source sequence(s)
    AB040137
    Consensus CDS
    CCDS25305.1
    UniProtKB/Swiss-Prot
    A2A6D6, Q9JHH9
    UniProtKB/TrEMBL
    Q9CTG7
    Related
    ENSMUSP00000018816.8, ENSMUST00000018816.14
    Conserved Domains (1) summary
    cl02092
    Location:40174
    Clat_adaptor_s; Clathrin adaptor complex small chain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    96740702..96752029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)