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fras1 Fraser extracellular matrix complex subunit 1 [ Danio rerio (zebrafish) ]

Gene ID: 563428, updated on 6-May-2021

Summary

Official Symbol
fras1provided by ZNC
Official Full Name
Fraser extracellular matrix complex subunit 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-060526-68
See related
Ensembl:ENSDARG00000054619
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
p; pif; id:ibd50; id:ibd5080; wu:fc10b09; si:ch211-191a6.5
Orthologs
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Genomic context

See fras1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
75
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (38837164..39086779)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (38237004..38486615)
103 previous assembly Zv9 (GCF_000002035.4) 5 NC_007116.5 (40437675..40687236)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene C-X-C motif chemokine ligand 13 Neighboring gene CCR4-NOT transcription complex, subunit 6-like Neighboring gene mitochondrial ribosomal protein L1 Neighboring gene annexin A3a Neighboring gene BMP2 inducible kinase

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

General gene information

Markers

Homology

General protein information

Preferred Names
extracellular matrix protein FRAS1
Names
Fraser syndrome 1
pinfin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130840.1NP_001124312.1  extracellular matrix protein FRAS1

    Status: PROVISIONAL

    Source sequence(s)
    BX571800, BX640536, CR392333
    UniProtKB/TrEMBL
    F1Q633
    Related
    ENSDARP00000071316.5, ENSDART00000076845.7
    Conserved Domains (9) summary
    smart00261
    Location:571614
    FU; Furin-like repeats
    cd00064
    Location:725769
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    pfam00093
    Location:157214
    VWC; von Willebrand factor type C domain
    pfam00757
    Location:557735
    Furin-like; Furin-like cysteine rich region
    pfam14843
    Location:483638
    GF_recep_IV; Growth factor receptor domain IV
    pfam15913
    Location:395483
    Furin-like_2; Furin-like repeat, cysteine-rich
    pfam16184
    Location:22252370
    Cadherin_3; Cadherin-like
    cl02522
    Location:25172614
    Calx-beta; Calx-beta domain
    cl17735
    Location:339385
    VWC; von Willebrand factor type C domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    38837164..39086779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009301656.3XP_009299931.1  extracellular matrix protein FRAS1 isoform X2

    UniProtKB/TrEMBL
    A0A0R4IQJ3
    Related
    ENSDARP00000088628.3, ENSDART00000097856.5
    Conserved Domains (9) summary
    smart00261
    Location:754796
    FU; Furin-like repeats
    cd00064
    Location:419465
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    pfam00093
    Location:157214
    VWC; von Willebrand factor type C domain
    pfam00757
    Location:588762
    Furin-like; Furin-like cysteine rich region
    pfam14843
    Location:512669
    GF_recep_IV; Growth factor receptor domain IV
    pfam15913
    Location:424512
    Furin-like_2; Furin-like repeat, cysteine-rich
    pfam16184
    Location:22572402
    Cadherin_3; Cadherin-like
    cl02522
    Location:25492646
    Calx-beta; Calx-beta domain
    cl17735
    Location:364414
    VWC; von Willebrand factor type C domain
  2. XM_021476261.1XP_021331936.1  extracellular matrix protein FRAS1 isoform X3

    Conserved Domains (7) summary
    cd00064
    Location:419465
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    pfam00093
    Location:157214
    VWC; von Willebrand factor type C domain
    pfam15913
    Location:424512
    Furin-like_2; Furin-like repeat, cysteine-rich
    pfam16184
    Location:22832392
    Cadherin_3; Cadherin-like
    cl02522
    Location:27583033
    Calx-beta; Calx-beta domain
    cl17735
    Location:364414
    VWC; von Willebrand factor type C domain
    cl28643
    Location:516888
    VSP; Giardia variant-specific surface protein
  3. XM_005165335.4XP_005165392.1  extracellular matrix protein FRAS1 isoform X1

    Related
    ENSDARP00000138474.2, ENSDART00000160236.2
    Conserved Domains (9) summary
    smart00261
    Location:754796
    FU; Furin-like repeats
    cd00064
    Location:419465
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    pfam00093
    Location:157214
    VWC; von Willebrand factor type C domain
    pfam00757
    Location:588762
    Furin-like; Furin-like cysteine rich region
    pfam14843
    Location:512669
    GF_recep_IV; Growth factor receptor domain IV
    pfam15913
    Location:424512
    Furin-like_2; Furin-like repeat, cysteine-rich
    pfam16184
    Location:22582403
    Cadherin_3; Cadherin-like
    cl02522
    Location:25502647
    Calx-beta; Calx-beta domain
    cl17735
    Location:364414
    VWC; von Willebrand factor type C domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394598.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    235197..425207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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