ap3b1a adaptor related protein complex 3 subunit beta 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ap3b1aprovided by ZNC
Official Full Name: adaptor related protein complex 3 subunit beta 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-031112-8
See related: AllianceGenome:ZFIN:ZDB-GENE-031112-8
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ap3b1; cb964
Summary: Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in clathrin-coated vesicle membrane. Predicted to be part of AP-3 adaptor complex and clathrin adaptor complex. Is expressed in several structures, including axial vasculature; intermediate cell mass of mesoderm; optic vesicle; ventral mesoderm; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome; Hermansky-Pudlak syndrome 2; interstitial lung disease; neutropenia; and pulmonary fibrosis. Orthologous to human AP3B1 (adaptor related protein complex 3 subunit beta 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	21	NC_133196.1 (8645025..8792685)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (7298573..7440389)

Chromosome 21 - NC_133196.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Process	Evidence Code	Pubs
involved_in anterograde synaptic vesicle transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of AP-3 adaptor complex	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
part_of clathrin adaptor complex	IEA Inferred from Electronic Annotation more info
located_in clathrin-coated vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of membrane coat	IEA Inferred from Electronic Annotation more info

Names: adaptor related protein complex 3 beta 1 subunit; adaptor-related protein complex 3, beta 1 subunit a

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_021469001.3 → XP_021324676.2 AP-3 complex subunit beta-1 isoform X3

UniProtKB/TrEMBL

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XM_073935772.1 → XP_073791873.1 AP-3 complex subunit beta-1 isoform X4

UniProtKB/TrEMBL

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XM_073935770.1 → XP_073791871.1 AP-3 complex subunit beta-1 isoform X1

UniProtKB/TrEMBL

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XM_073935771.1 → XP_073791872.1 AP-3 complex subunit beta-1 isoform X2

UniProtKB/TrEMBL

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