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Fkbpl FK506 binding protein-like [ Mus musculus (house mouse) ]

Gene ID: 56299, updated on 8-Feb-2024

Summary

Official Symbol
Fkbplprovided by MGI
Official Full Name
FK506 binding protein-likeprovided by MGI
Primary source
MGI:MGI:1932127
See related
Ensembl:ENSMUSG00000033739 AllianceGenome:MGI:1932127
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NG7; DIR1; Wisp39; Ppiase-X
Summary
Acts upstream of or within regulation of blood vessel branching. Predicted to be located in extracellular region. Is expressed in several structures, including eye; gut; hemolymphoid system; male reproductive gland or organ; and nervous system. Orthologous to human FKBPL (FKBP prolyl isomerase like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 17.6), colon adult (RPKM 3.5) and 23 other tissues See more
Orthologs
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Genomic context

See Fkbpl in Genome Data Viewer
Location:
17 B1; 17 18.22 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (34863788..34865791)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (34644814..34646817)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2610029K11 gene Neighboring gene palmitoyl-protein thioesterase 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:34767227-34767451 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:34768061-34768244 Neighboring gene proline-rich transmembrane protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E770 Neighboring gene STARR-positive B cell enhancer ABC_E4212 Neighboring gene activating transcription factor 6 beta Neighboring gene tenascin XB Neighboring gene predicted gene, 24389

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
FK506-binding protein-like
Names
WAF-1/CIP1 stabilizing protein 39
immunophilin-like protein NG7
NP_063926.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019873.3NP_063926.1  FK506-binding protein-like

    See identical proteins and their annotated locations for NP_063926.1

    Status: VALIDATED

    Source sequence(s)
    AK146018, CD776267, CT009767
    Consensus CDS
    CCDS28654.1
    UniProtKB/Swiss-Prot
    O35450, Q3UKG5
    Related
    ENSMUSP00000037273.9, ENSMUST00000036720.9
    Conserved Domains (3) summary
    COG0457
    Location:203316
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:208236
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:285317
    TPR_1; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    34863788..34865791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)