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Dipk1b divergent protein kinase domain 1B [ Mus musculus (house mouse) ]

Gene ID: 56279, updated on 5-Mar-2024

Summary

Official Symbol
Dipk1bprovided by MGI
Official Full Name
divergent protein kinase domain 1Bprovided by MGI
Primary source
MGI:MGI:1927576
See related
Ensembl:ENSMUSG00000036186 AllianceGenome:MGI:1927576
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PIP49; Fam69b; B230317C12Rik
Summary
Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in early conceptus and secondary oocyte. Orthologous to human DIPK1B (divergent protein kinase domain 1B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 33.9), CNS E18 (RPKM 33.2) and 23 other tissues See more
Orthologs
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Genomic context

See Dipk1b in Genome Data Viewer
Location:
2 A3; 2 18.97 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26518469..26526509)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26628457..26636497)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 Neighboring gene STARR-seq mESC enhancer starr_03989 Neighboring gene predicted gene, 39772 Neighboring gene small nucleolar RNA, H/ACA box 43 Neighboring gene small nucleolar RNA host gene 7 Neighboring gene small nucleolar RNA, H/ACA box 17

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

General gene information

Markers

Potential readthrough

Included gene: Egfl7

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
divergent protein kinase domain 1B
Names
family with sequence similarity 69, member B
pancreatitis-induced protein 49
protein FAM69B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019833.3NP_062807.2  divergent protein kinase domain 1B

    See identical proteins and their annotated locations for NP_062807.2

    Status: VALIDATED

    Source sequence(s)
    AI840756, AK045880
    Consensus CDS
    CCDS50542.1
    UniProtKB/Swiss-Prot
    Q0VG43, Q80UM6, Q99ML4, Q9JMG0
    Related
    ENSMUSP00000073860.4, ENSMUST00000074240.4
    Conserved Domains (2) summary
    pfam12260
    Location:198399
    PIP49_C; Protein-kinase domain of FAM69
    pfam14875
    Location:23179
    PIP49_N; N-term cysteine-rich ER, FAM69

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    26518469..26526509
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)